BRD-K21773564_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

90 genes differentially expressed following the BRD-K21773564_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
BTG2 BTG family, member 2
C1ORF54 chromosome 1 open reading frame 54
C8ORF4 chromosome 8 open reading frame 4
CCL20 chemokine (C-C motif) ligand 20
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CTH cystathionine gamma-lyase
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DENND1B DENN/MADD domain containing 1B
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
FBXL14 F-box and leucine-rich repeat protein 14
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GRAMD3 GRAM domain containing 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
IL6 interleukin 6
INSIG1 insulin induced gene 1
JCHAIN joining chain of multimeric IgA and IgM
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
MAOB monoamine oxidase B
MMP1 matrix metallopeptidase 1
MT1M metallothionein 1M
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
ODC1 ornithine decarboxylase 1
PLK2 polo-like kinase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RGS2 regulator of G-protein signaling 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A2 solute carrier family 38, member 2
SPINK1 serine peptidase inhibitor, Kazal type 1
STK38L serine/threonine kinase 38 like
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOB1 transducer of ERBB2, 1
TSPYL2 TSPY-like 2
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CCND1 cyclin D1
CCNF cyclin F
CD24 CD24 molecule
CD99 CD99 molecule
CDCA4 cell division cycle associated 4
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLU clusterin
DAPK1 death-associated protein kinase 1
ENO1 enolase 1, (alpha)
FSTL1 follistatin-like 1
IFITM3 interferon induced transmembrane protein 3
KRT4 keratin 4, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LYZ lysozyme
MARCKS myristoylated alanine-rich protein kinase C substrate
PSPH phosphoserine phosphatase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SET SET nuclear proto-oncogene
SPRR1A small proline-rich protein 1A
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TFF1 trefoil factor 1
TM4SF1 transmembrane 4 L six family member 1
TNS3 tensin 3
TUBB tubulin, beta class I