BRD-K21786893_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools


39 genes differentially expressed following the BRD-K21786893_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL4 chemokine (C-C motif) ligand 4
CD14 CD14 molecule
COLEC12 collectin sub-family member 12
GSAP gamma-secretase activating protein
GSTA4 glutathione S-transferase alpha 4
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS8 lectin, galactoside-binding, soluble, 8
SNCA synuclein, alpha (non A4 component of amyloid precursor)

decreased expression

Symbol Name
APOLD1 apolipoprotein L domain containing 1
AREG amphiregulin
ASCL1 achaete-scute family bHLH transcription factor 1
CCND2 cyclin D2
COL14A1 collagen, type XIV, alpha 1
DARS aspartyl-tRNA synthetase
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
HIST1H4C histone cluster 1, H4c
HRSP12 heat-responsive protein 12
IGF1R insulin-like growth factor 1 receptor
LARP1 La ribonucleoprotein domain family, member 1
LMO3 LIM domain only 3 (rhombotin-like 2)
MME membrane metallo-endopeptidase
MT1G metallothionein 1G
MT1X metallothionein 1X
MTDH metadherin
PLCB4 phospholipase C, beta 4
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PROSC proline synthetase co-transcribed homolog (bacterial)
RAP2A RAP2A, member of RAS oncogene family
SFRP1 secreted frizzled-related protein 1
SQLE squalene epoxidase
TFPI2 tissue factor pathway inhibitor 2
WDTC1 WD and tetratricopeptide repeats 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta