BRD-K22134346_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

87 genes differentially expressed following the BRD-K22134346_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
BST2 bone marrow stromal cell antigen 2
BTG2 BTG family, member 2
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CPB1 carboxypeptidase B1 (tissue)
CPM carboxypeptidase M
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ERBB3 erb-b2 receptor tyrosine kinase 3
FAXDC2 fatty acid hydroxylase domain containing 2
GCHFR GTP cyclohydrolase I feedback regulator
GREB1 growth regulation by estrogen in breast cancer 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
IFITM1 interferon induced transmembrane protein 1
LEF1 lymphoid enhancer-binding factor 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MMP12 matrix metallopeptidase 12
MT1G metallothionein 1G
MT1H metallothionein 1H
MTMR11 myotubularin related protein 11
MYB v-myb avian myeloblastosis viral oncogene homolog
NQO1 NAD(P)H dehydrogenase, quinone 1
RAB31 RAB31, member RAS oncogene family
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD7 SMAD family member 7
TBXA2R thromboxane A2 receptor
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TSPAN7 tetraspanin 7
TSPAN8 tetraspanin 8
TXNIP thioredoxin interacting protein
WWP1 WW domain containing E3 ubiquitin protein ligase 1

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
CD59 CD59 molecule, complement regulatory protein
CDC42 cell division cycle 42
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL1A1 collagen, type I, alpha 1
CP ceruloplasmin (ferroxidase)
CTSG cathepsin G
CX3CR1 chemokine (C-X3-C motif) receptor 1
DUSP6 dual specificity phosphatase 6
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
FSTL1 follistatin-like 1
HILPDA hypoxia inducible lipid droplet-associated
HOMER3 homer scaffolding protein 3
KRT17 keratin 17, type I
KRT23 keratin 23, type I
KRT5 keratin 5, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LOX lysyl oxidase
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MCL1 myeloid cell leukemia 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIB nuclear factor I/B
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NNMT nicotinamide N-methyltransferase
PFN2 profilin 2
PI3 peptidase inhibitor 3, skin-derived
PLK2 polo-like kinase 2
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTX3 pentraxin 3, long
PXDN peroxidasin
RAB2A RAB2A, member RAS oncogene family
RHOB ras homolog family member B
RHOBTB3 Rho-related BTB domain containing 3
RND3 Rho family GTPase 3
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLPI secretory leukocyte peptidase inhibitor
SNX7 sorting nexin 7
SPATS2L spermatogenesis associated, serine-rich 2-like
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM4SF1 transmembrane 4 L six family member 1
TPM1 tropomyosin 1 (alpha)
VCAN versican