| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
114 genes differentially expressed following the BRD-K22215695_1-(4-methylbenzyl)-4-[4-(2-methylphenyl)-1-piperazinyl]-1H-pyrazolo[3,4-d]pyrimidine_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADIRF | adipogenesis regulatory factor |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ANPEP | alanyl (membrane) aminopeptidase |
| ATF3 | activating transcription factor 3 |
| ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) |
| BCL2A1 | BCL2-related protein A1 |
| CA12 | carbonic anhydrase XII |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CKLF | chemokine-like factor |
| CNPY3 | canopy FGF signaling regulator 3 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CYBRD1 | cytochrome b reductase 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EPN2 | epsin 2 |
| EREG | epiregulin |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FBXL12 | F-box and leucine-rich repeat protein 12 |
| FBXO11 | F-box protein 11 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL17RB | interleukin 17 receptor B |
| JUN | jun proto-oncogene |
| KLF4 | Kruppel-like factor 4 (gut) |
| KRT19 | keratin 19, type I |
| KRT7 | keratin 7, type II |
| LRRC17 | leucine rich repeat containing 17 |
| MLF1 | myeloid leukemia factor 1 |
| MLPH | melanophilin |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEBL | nebulette |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRUNE2 | prune homolog 2 (Drosophila) |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RGCC | regulator of cell cycle |
| RGS2 | regulator of G-protein signaling 2 |
| S100A11 | S100 calcium binding protein A11 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SOAT1 | sterol O-acyltransferase 1 |
| STC2 | stanniocalcin 2 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TFF3 | trefoil factor 3 (intestinal) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TSC22D1 | TSC22 domain family, member 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| TUBA1A | tubulin, alpha 1a |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| Symbol | Name |
|---|---|
| ADCY1 | adenylate cyclase 1 (brain) |
| AIM1 | absent in melanoma 1 |
| ANKRD10 | ankyrin repeat domain 10 |
| ANKRD28 | ankyrin repeat domain 28 |
| AUTS2 | autism susceptibility candidate 2 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CLC | Charcot-Leyden crystal galectin |
| CLEC11A | C-type lectin domain family 11, member A |
| CUL1 | cullin 1 |
| DUSP22 | dual specificity phosphatase 22 |
| ELANE | elastase, neutrophil expressed |
| FASTKD5 | FAST kinase domains 5 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLS | glutaminase |
| GOLGA8A | golgin A8 family, member A |
| GTF2E2 | general transcription factor IIE, polypeptide 2, beta 34kDa |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HK1 | hexokinase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LXN | latexin |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MDFIC | MyoD family inhibitor domain containing |
| MLXIP | MLX interacting protein |
| MMP9 | matrix metallopeptidase 9 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| NUP50 | nucleoporin 50kDa |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PDS5A | PDS5 cohesin associated factor A |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTPRK | protein tyrosine phosphatase, receptor type, K |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RRP1B | ribosomal RNA processing 1B |
| RUNX3 | runt-related transcription factor 3 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SESN1 | sestrin 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TGFB1 | transforming growth factor, beta 1 |
| TMEM45A | transmembrane protein 45A |
| TMEM5 | transmembrane protein 5 |
| TOMM70A | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 |
| UBE3C | ubiquitin protein ligase E3C |
