BRD-K23027438_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-K23027438_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
ALDOC aldolase C, fructose-bisphosphate
BIRC3 baculoviral IAP repeat containing 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C6ORF62 chromosome 6 open reading frame 62
CCL20 chemokine (C-C motif) ligand 20
CELF2 CUGBP, Elav-like family member 2
CTSZ cathepsin Z
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
EIF5A eukaryotic translation initiation factor 5A
GCLM glutamate-cysteine ligase, modifier subunit
GPM6B glycoprotein M6B
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
KDM3A lysine (K)-specific demethylase 3A
MT1F metallothionein 1F
MT1M metallothionein 1M
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PRPF4 pre-mRNA processing factor 4
SAT1 spermidine/spermine N1-acetyltransferase 1
SELE selectin E
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SQSTM1 sequestosome 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIP1 TNFAIP3 interacting protein 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
XBP1 X-box binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CPE carboxypeptidase E
FGB fibrinogen beta chain
FGFR3 fibroblast growth factor receptor 3
KRT18 keratin 18, type I
LYPD1 LY6/PLAUR domain containing 1
MEIS1 Meis homeobox 1
PERP PERP, TP53 apoptosis effector
PITX1 paired-like homeodomain 1
PLK1 polo-like kinase 1
QPCT glutaminyl-peptide cyclotransferase
RGS5 regulator of G-protein signaling 5
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SPINK1 serine peptidase inhibitor, Kazal type 1
SPON2 spondin 2, extracellular matrix protein
TSPAN13 tetraspanin 13
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28