BRD-K23931216_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K23931216_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOC1 apolipoprotein C-I
ARG2 arginase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CA2 carbonic anhydrase II
CDKN2A cyclin-dependent kinase inhibitor 2A
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHMP4A charged multivesicular body protein 4A
CTH cystathionine gamma-lyase
EPHA4 EPH receptor A4
EXT1 exostosin glycosyltransferase 1
FN1 fibronectin 1
GEM GTP binding protein overexpressed in skeletal muscle
GPX3 glutathione peroxidase 3
HSPA1A heat shock 70kDa protein 1A
LOC100505650 uncharacterized LOC100505650
MFSD10 major facilitator superfamily domain containing 10
NPTX2 neuronal pentraxin II
NUPR1 nuclear protein, transcriptional regulator, 1
PDE4D phosphodiesterase 4D, cAMP-specific
RAB4A RAB4A, member RAS oncogene family
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
SOD2 superoxide dismutase 2, mitochondrial
STC2 stanniocalcin 2
TFPI2 tissue factor pathway inhibitor 2
TMEM47 transmembrane protein 47
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPD52L1 tumor protein D52-like 1
TRIM2 tripartite motif containing 2

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
ASPN asporin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK1 death-associated protein kinase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPYSL3 dihydropyrimidinase-like 3
ECM1 extracellular matrix protein 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
F13A1 coagulation factor XIII, A1 polypeptide
FST follistatin
FXYD3 FXYD domain containing ion transport regulator 3
GAS6 growth arrest-specific 6
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IPO7 importin 7
IQGAP1 IQ motif containing GTPase activating protein 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
LAMB1 laminin, beta 1
LAMP5 lysosomal-associated membrane protein family, member 5
MEIS2 Meis homeobox 2
MFAP2 microfibrillar-associated protein 2
MFAP5 microfibrillar associated protein 5
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
NUP62 nucleoporin 62kDa
PIP prolactin-induced protein
PRKCD protein kinase C, delta
RBPMS RNA binding protein with multiple splicing
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SDC1 syndecan 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TACSTD2 tumor-associated calcium signal transducer 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNS1 tensin 1
TSPAN8 tetraspanin 8