| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
104 genes differentially expressed following the BRD-K23984367_sorafenib_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACLY | ATP citrate lyase |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| AUTS2 | autism susceptibility candidate 2 |
| BLVRB | biliverdin reductase B |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CBR3 | carbonyl reductase 3 |
| CD14 | CD14 molecule |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHI3L2 | chitinase 3-like 2 |
| CKB | creatine kinase, brain |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CSTA | cystatin A (stefin A) |
| DACH1 | dachshund family transcription factor 1 |
| DHCR7 | 7-dehydrocholesterol reductase |
| DST | dystonin |
| DSTN | destrin (actin depolymerizing factor) |
| EPHB2 | EPH receptor B2 |
| FCGBP | Fc fragment of IgG binding protein |
| FOXG1 | forkhead box G1 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GLUL | glutamate-ammonia ligase |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) |
| HMOX1 | heme oxygenase 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IGHD | immunoglobulin heavy constant delta |
| IGHM | immunoglobulin heavy constant mu |
| IL7R | interleukin 7 receptor |
| LEFTY1 | left-right determination factor 1 |
| NAMPT | nicotinamide phosphoribosyltransferase |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NEBL | nebulette |
| OLFM4 | olfactomedin 4 |
| PGD | phosphogluconate dehydrogenase |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| RAB40B | RAB40B, member RAS oncogene family |
| REG1A | regenerating islet-derived 1 alpha |
| REG3A | regenerating islet-derived 3 alpha |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SIRT3 | sirtuin 3 |
| SNCAIP | synuclein, alpha interacting protein |
| SORD | sorbitol dehydrogenase |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| TCAF1 | TRPM8 channel-associated factor 1 |
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| AEBP1 | AE binding protein 1 |
| AHR | aryl hydrocarbon receptor |
| ANXA1 | annexin A1 |
| ARHGAP29 | Rho GTPase activating protein 29 |
| BACE2 | beta-site APP-cleaving enzyme 2 |
| BTG3 | BTG family, member 3 |
| CLEC11A | C-type lectin domain family 11, member A |
| CLGN | calmegin |
| COL10A1 | collagen, type X, alpha 1 |
| COL11A1 | collagen, type XI, alpha 1 |
| CTGF | connective tissue growth factor |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| CYTL1 | cytokine-like 1 |
| DUSP6 | dual specificity phosphatase 6 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FGF13 | fibroblast growth factor 13 |
| FST | follistatin |
| GOLGA8A | golgin A8 family, member A |
| HDAC9 | histone deacetylase 9 |
| HOXB2 | homeobox B2 |
| IER3 | immediate early response 3 |
| IFRD2 | interferon-related developmental regulator 2 |
| ITM2A | integral membrane protein 2A |
| KLK10 | kallikrein-related peptidase 10 |
| KRT23 | keratin 23, type I |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 |
| MEF2C | myocyte enhancer factor 2C |
| MFAP5 | microfibrillar associated protein 5 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFIB | nuclear factor I/B |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PEG3 | paternally expressed 3 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PRSS21 | protease, serine, 21 (testisin) |
| S100P | S100 calcium binding protein P |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SGCE | sarcoglycan, epsilon |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| THBS1 | thrombospondin 1 |
| THBS2 | thrombospondin 2 |
| VIM | vimentin |
| ZBED2 | zinc finger, BED-type containing 2 |
