BRD-K24132293_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K24132293_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ALCAM activated leukocyte cell adhesion molecule
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
C4BPA complement component 4 binding protein, alpha
CSRP1 cysteine and glycine-rich protein 1
CTSZ cathepsin Z
CYR61 cysteine-rich, angiogenic inducer, 61
DEPTOR DEP domain containing MTOR-interacting protein
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A eukaryotic translation initiation factor 5A
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FTH1 ferritin, heavy polypeptide 1
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
H2BFS H2B histone family, member S (pseudogene)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HIST1H2AE histone cluster 1, H2ae
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
ITGB4 integrin, beta 4
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KIAA0226L KIAA0226-like
MYO6 myosin VI
NR4A1 nuclear receptor subfamily 4, group A, member 1
NT5E 5'-nucleotidase, ecto (CD73)
RGS2 regulator of G-protein signaling 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SQRDL sulfide quinone reductase-like (yeast)
SRSF7 serine/arginine-rich splicing factor 7
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM255A transmembrane protein 255A
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADRB2 adrenoceptor beta 2, surface
ASCL1 achaete-scute family bHLH transcription factor 1
AUTS2 autism susceptibility candidate 2
C1ORF116 chromosome 1 open reading frame 116
CAST calpastatin
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CRISP3 cysteine-rich secretory protein 3
CSTA cystatin A (stefin A)
CTSC cathepsin C
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DACH1 dachshund family transcription factor 1
DCLK1 doublecortin-like kinase 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM198B family with sequence similarity 198, member B
FOSL1 FOS-like antigen 1
HSPB8 heat shock 22kDa protein 8
IL1RN interleukin 1 receptor antagonist
JAG1 jagged 1
LPAR6 lysophosphatidic acid receptor 6
MARCKS myristoylated alanine-rich protein kinase C substrate
NFIB nuclear factor I/B
PCNA proliferating cell nuclear antigen
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RET ret proto-oncogene
RIN2 Ras and Rab interactor 2
S100P S100 calcium binding protein P
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFRP1 secreted frizzled-related protein 1
SLPI secretory leukocyte peptidase inhibitor
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SOBP sine oculis binding protein homolog (Drosophila)
SYT1 synaptotagmin I
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TMEM47 transmembrane protein 47
TOX3 TOX high mobility group box family member 3