| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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90 genes differentially expressed following the BRD-K24426149_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ABHD4 | abhydrolase domain containing 4 |
| ADAM28 | ADAM metallopeptidase domain 28 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ATF3 | activating transcription factor 3 |
| C3 | complement component 3 |
| CFB | complement factor B |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHI3L2 | chitinase 3-like 2 |
| CLU | clusterin |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| FTH1 | ferritin, heavy polypeptide 1 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GRAMD3 | GRAM domain containing 3 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HMOX1 | heme oxygenase 1 |
| HPSE | heparanase |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IGKV4-1 | immunoglobulin kappa variable 4-1 |
| JUN | jun proto-oncogene |
| LXN | latexin |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| PIR | pirin (iron-binding nuclear protein) |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| RBP1 | retinol binding protein 1, cellular |
| RHOB | ras homolog family member B |
| RNF167 | ring finger protein 167 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SQSTM1 | sequestosome 1 |
| TBP | TATA box binding protein |
| TXNL1 | thioredoxin-like 1 |
| TXNRD1 | thioredoxin reductase 1 |
| UGDH | UDP-glucose 6-dehydrogenase |
| XBP1 | X-box binding protein 1 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ANXA3 | annexin A3 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CHGB | chromogranin B |
| CHRDL1 | chordin-like 1 |
| COL1A2 | collagen, type I, alpha 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| EXT1 | exostosin glycosyltransferase 1 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FBXL12 | F-box and leucine-rich repeat protein 12 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GNAS | GNAS complex locus |
| IFI16 | interferon, gamma-inducible protein 16 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| LAMB1 | laminin, beta 1 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LYZ | lysozyme |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MKI67 | marker of proliferation Ki-67 |
| MX1 | MX dynamin-like GTPase 1 |
| MX2 | MX dynamin-like GTPase 2 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| REG1A | regenerating islet-derived 1 alpha |
| RGS5 | regulator of G-protein signaling 5 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| TFF1 | trefoil factor 1 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPM1 | tropomyosin 1 (alpha) |
| TPM2 | tropomyosin 2 (beta) |
| VCAN | versican |
| ZNF91 | zinc finger protein 91 |
