Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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103 genes differentially expressed following the BRD-K24496482_SB590885_HCC515_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
ADGRL2 | adhesion G protein-coupled receptor L2 |
AGR2 | anterior gradient 2 |
ANXA1 | annexin A1 |
ARL4C | ADP-ribosylation factor-like 4C |
C3ORF14 | chromosome 3 open reading frame 14 |
CCND1 | cyclin D1 |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CDKN2A | cyclin-dependent kinase inhibitor 2A |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 |
DUSP4 | dual specificity phosphatase 4 |
DUSP6 | dual specificity phosphatase 6 |
EGR1 | early growth response 1 |
EPHA2 | EPH receptor A2 |
ETV1 | ets variant 1 |
ETV5 | ets variant 5 |
FOSL1 | FOS-like antigen 1 |
GEM | GTP binding protein overexpressed in skeletal muscle |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
HMGA2 | high mobility group AT-hook 2 |
IL6 | interleukin 6 |
ISG20 | interferon stimulated exonuclease gene 20kDa |
JUN | jun proto-oncogene |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MGLL | monoglyceride lipase |
MOXD1 | monooxygenase, DBH-like 1 |
NEBL | nebulette |
NPAS2 | neuronal PAS domain protein 2 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
NT5E | 5'-nucleotidase, ecto (CD73) |
P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
PDLIM4 | PDZ and LIM domain 4 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PMP22 | peripheral myelin protein 22 |
PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
PTX3 | pentraxin 3, long |
RGS4 | regulator of G-protein signaling 4 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SFRP1 | secreted frizzled-related protein 1 |
SLIT2 | slit homolog 2 (Drosophila) |
SMAD3 | SMAD family member 3 |
SMS | spermine synthase |
SOX9 | SRY (sex determining region Y)-box 9 |
SPP1 | secreted phosphoprotein 1 |
SPRY4 | sprouty homolog 4 (Drosophila) |
STX1A | syntaxin 1A (brain) |
STXBP2 | syntaxin binding protein 2 |
SVIL | supervillin |
TGFA | transforming growth factor, alpha |
TM4SF1 | transmembrane 4 L six family member 1 |
TUBB2A | tubulin, beta 2A class IIa |
WLS | wntless Wnt ligand secretion mediator |
WNT5A | wingless-type MMTV integration site family, member 5A |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
ACTA2 | actin, alpha 2, smooth muscle, aorta |
ACTG2 | actin, gamma 2, smooth muscle, enteric |
ADA | adenosine deaminase |
ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide |
C5 | complement component 5 |
CA1 | carbonic anhydrase I |
CA12 | carbonic anhydrase XII |
CD14 | CD14 molecule |
CFD | complement factor D (adipsin) |
COL3A1 | collagen, type III, alpha 1 |
CP | ceruloplasmin (ferroxidase) |
CPE | carboxypeptidase E |
CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
F13A1 | coagulation factor XIII, A1 polypeptide |
FGB | fibrinogen beta chain |
GIMAP6 | GTPase, IMAP family member 6 |
GPER1 | G protein-coupled estrogen receptor 1 |
HBB | hemoglobin, beta |
HSPA2 | heat shock 70kDa protein 2 |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
IFITM2 | interferon induced transmembrane protein 2 |
IFITM3 | interferon induced transmembrane protein 3 |
IGF1 | insulin-like growth factor 1 (somatomedin C) |
ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
ITM2A | integral membrane protein 2A |
KIF14 | kinesin family member 14 |
MUC1 | mucin 1, cell surface associated |
MYB | v-myb avian myeloblastosis viral oncogene homolog |
MYLK | myosin light chain kinase |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
PAWR | PRKC, apoptosis, WT1, regulator |
PDZK1 | PDZ domain containing 1 |
PECR | peroxisomal trans-2-enoyl-CoA reductase |
PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
QPRT | quinolinate phosphoribosyltransferase |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
S100A8 | S100 calcium binding protein A8 |
SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
TAGLN | transgelin |
VDAC1 | voltage-dependent anion channel 1 |