BRD-K24496482_SB590885_SKBR3_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K24496482_SB590885_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AHNAK AHNAK nucleoprotein
ALDOB aldolase B, fructose-bisphosphate
AQP3 aquaporin 3 (Gill blood group)
C6ORF62 chromosome 6 open reading frame 62
CCL2 chemokine (C-C motif) ligand 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CERS2 ceramide synthase 2
CSRP2 cysteine and glycine-rich protein 2
CTGF connective tissue growth factor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
F3 coagulation factor III (thromboplastin, tissue factor)
FAM129A family with sequence similarity 129, member A
FBLN1 fibulin 1
FHL2 four and a half LIM domains 2
FOXF1 forkhead box F1
GDF15 growth differentiation factor 15
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ISG15 ISG15 ubiquitin-like modifier
KLF4 Kruppel-like factor 4 (gut)
LITAF lipopolysaccharide-induced TNF factor
MSMB microseminoprotein, beta-
MX1 MX dynamin-like GTPase 1
OLFM4 olfactomedin 4
PALLD palladin, cytoskeletal associated protein
PMP2 peripheral myelin protein 2
PMP22 peripheral myelin protein 22
RHOB ras homolog family member B
S100P S100 calcium binding protein P
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SGK1 serum/glucocorticoid regulated kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORD sorbitol dehydrogenase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUBB2A tubulin, beta 2A class IIa
VAV3 vav 3 guanine nucleotide exchange factor
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
C10ORF10 chromosome 10 open reading frame 10
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CHGB chromogranin B
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GRB7 growth factor receptor-bound protein 7
JADE2 jade family PHD finger 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM5D lysine (K)-specific demethylase 5D
KRT14 keratin 14, type I
MXRA7 matrix-remodelling associated 7
NCK1 NCK adaptor protein 1
PLA2G16 phospholipase A2, group XVI
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SCG5 secretogranin V
SCGB1D2 secretoglobin, family 1D, member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
Funding