BRD-K24515980_QL-XI-92_HEPG2_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K24515980_QL-XI-92_HEPG2_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADGRG6 adhesion G protein-coupled receptor G6
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
CCR7 chemokine (C-C motif) receptor 7
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD9 CD9 molecule
CLEC2B C-type lectin domain family 2, member B
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
DST dystonin
EDNRB endothelin receptor type B
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM129A family with sequence similarity 129, member A
GATA3 GATA binding protein 3
GEM GTP binding protein overexpressed in skeletal muscle
ITGA6 integrin, alpha 6
JAG1 jagged 1
KRT5 keratin 5, type II
LRRN3 leucine rich repeat neuronal 3
LXN latexin
MEIS2 Meis homeobox 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PTPRC protein tyrosine phosphatase, receptor type, C
RGS1 regulator of G-protein signaling 1
S100A2 S100 calcium binding protein A2
S100P S100 calcium binding protein P
SFN stratifin
SPATS2L spermatogenesis associated, serine-rich 2-like
STK10 serine/threonine kinase 10
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNC tenascin C
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOMM34 translocase of outer mitochondrial membrane 34
TSPAN13 tetraspanin 13
UGCG UDP-glucose ceramide glucosyltransferase
VCL vinculin

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMACR alpha-methylacyl-CoA racemase
ARID1A AT rich interactive domain 1A (SWI-like)
ASS1 argininosuccinate synthase 1
BPHL biphenyl hydrolase-like (serine hydrolase)
C1S complement component 1, s subcomponent
CD79A CD79a molecule, immunoglobulin-associated alpha
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLDN3 claudin 3
CRABP1 cellular retinoic acid binding protein 1
FABP1 fatty acid binding protein 1, liver
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GLUL glutamate-ammonia ligase
GSE1 Gse1 coiled-coil protein
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGKV3-20 immunoglobulin kappa variable 3-20
KIF5C kinesin family member 5C
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
POU2AF1 POU class 2 associating factor 1
PROM1 prominin 1
RRM2 ribonucleotide reductase M2
S100A12 S100 calcium binding protein A12
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SELENBP1 selenium binding protein 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOCS1 suppressor of cytokine signaling 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TKT transketolase
TMEM97 transmembrane protein 97
TMSB15A thymosin beta 15a
TOX3 TOX high mobility group box family member 3
WNT5A wingless-type MMTV integration site family, member 5A
ZMYM2 zinc finger, MYM-type 2