BRD-K24705176_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

73 genes differentially expressed following the BRD-K24705176_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX5 arachidonate 5-lipoxygenase
ATP11B ATPase, class VI, type 11B
C5AR1 complement component 5a receptor 1
CA12 carbonic anhydrase XII
CCDC86 coiled-coil domain containing 86
CD52 CD52 molecule
CD69 CD69 molecule
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLU clusterin
CRISP3 cysteine-rich secretory protein 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYTH1 cytohesin 1
CYTIP cytohesin 1 interacting protein
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FXYD2 FXYD domain containing ion transport regulator 2
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPNMB glycoprotein (transmembrane) nmb
GSAP gamma-secretase activating protein
HES1 hes family bHLH transcription factor 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
ITM2A integral membrane protein 2A
KDM5D lysine (K)-specific demethylase 5D
KRT15 keratin 15, type I
MLPH melanophilin
MYO5C myosin VC
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTS neurotensin
PAN2 PAN2 poly(A) specific ribonuclease subunit
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
RAB4A RAB4A, member RAS oncogene family
RHOB ras homolog family member B
RNASE6 ribonuclease, RNase A family, k6
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMAD3 SMAD family member 3
SOCS2 suppressor of cytokine signaling 2
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TSKU tsukushi, small leucine rich proteoglycan
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase
WBP5 WW domain binding protein 5
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
AUTS2 autism susceptibility candidate 2
CDC42 cell division cycle 42
CDCA4 cell division cycle associated 4
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CPB1 carboxypeptidase B1 (tissue)
DUSP3 dual specificity phosphatase 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FAM46A family with sequence similarity 46, member A
FOLR1 folate receptor 1 (adult)
FOXG1 forkhead box G1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GNAS GNAS complex locus
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
NELL2 NEL-like 2 (chicken)
NLGN4X neuroligin 4, X-linked
RPS11 ribosomal protein S11
RTN2 reticulon 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLPI secretory leukocyte peptidase inhibitor
SYT11 synaptotagmin XI
TNNT1 troponin T type 1 (skeletal, slow)
VGLL1 vestigial-like family member 1
Funding