Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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114 genes differentially expressed following the BRD-K25737009_-666_A375_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ATF3 | activating transcription factor 3 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
CCL20 | chemokine (C-C motif) ligand 20 |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CLDN3 | claudin 3 |
CRABP2 | cellular retinoic acid binding protein 2 |
CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
DDIT3 | DNA-damage-inducible transcript 3 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DUSP1 | dual specificity phosphatase 1 |
EGR1 | early growth response 1 |
EIF5A | eukaryotic translation initiation factor 5A |
EPAS1 | endothelial PAS domain protein 1 |
FTH1 | ferritin, heavy polypeptide 1 |
GADD45A | growth arrest and DNA-damage-inducible, alpha |
GADD45B | growth arrest and DNA-damage-inducible, beta |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HIST1H1C | histone cluster 1, H1c |
HIST1H2BG | histone cluster 1, H2bg |
HMOX1 | heme oxygenase 1 |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
IER5 | immediate early response 5 |
ISG20 | interferon stimulated exonuclease gene 20kDa |
JUN | jun proto-oncogene |
JUNB | jun B proto-oncogene |
JUND | jun D proto-oncogene |
KLF4 | Kruppel-like factor 4 (gut) |
MMP1 | matrix metallopeptidase 1 |
MT1E | metallothionein 1E |
MT1F | metallothionein 1F |
MT1G | metallothionein 1G |
MT1H | metallothionein 1H |
MZB1 | marginal zone B and B1 cell-specific protein |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
NT5E | 5'-nucleotidase, ecto (CD73) |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
PYCARD | PYD and CARD domain containing |
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
SHB | Src homology 2 domain containing adaptor protein B |
TCEAL2 | transcription elongation factor A (SII)-like 2 |
VEGFA | vascular endothelial growth factor A |
XIST | X inactive specific transcript (non-protein coding) |
ZFP36 | ZFP36 ring finger protein |
Symbol | Name |
---|---|
ACACA | acetyl-CoA carboxylase alpha |
ACAT1 | acetyl-CoA acetyltransferase 1 |
AKAP7 | A kinase (PRKA) anchor protein 7 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
AMD1 | adenosylmethionine decarboxylase 1 |
ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 |
B3GNT1 | |
BST2 | bone marrow stromal cell antigen 2 |
CALU | calumenin |
CCNA2 | cyclin A2 |
CCND1 | cyclin D1 |
CCNG1 | cyclin G1 |
CD59 | CD59 molecule, complement regulatory protein |
CDC123 | cell division cycle 123 |
CDC42 | cell division cycle 42 |
CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
CHPT1 | choline phosphotransferase 1 |
CHSY1 | chondroitin sulfate synthase 1 |
CLIC4 | chloride intracellular channel 4 |
CLTC | clathrin, heavy chain (Hc) |
CPD | carboxypeptidase D |
CTR9 | CTR9, Paf1/RNA polymerase II complex component |
DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
ECI2 | enoyl-CoA delta isomerase 2 |
ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
FAM57A | family with sequence similarity 57, member A |
FSTL1 | follistatin-like 1 |
GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 |
GGNBP2 | gametogenetin binding protein 2 |
HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
HLTF | helicase-like transcription factor |
HN1L | hematological and neurological expressed 1-like |
HOXC6 | homeobox C6 |
ICMT | isoprenylcysteine carboxyl methyltransferase |
IFITM2 | interferon induced transmembrane protein 2 |
KDM5D | lysine (K)-specific demethylase 5D |
KLC1 | kinesin light chain 1 |
LAMC1 | laminin, gamma 1 (formerly LAMB2) |
LBR | lamin B receptor |
MAP7 | microtubule-associated protein 7 |
MKI67 | marker of proliferation Ki-67 |
MRFAP1L1 | Morf4 family associated protein 1-like 1 |
MRPS30 | mitochondrial ribosomal protein S30 |
MTCL1 | microtubule crosslinking factor 1 |
NOTCH2 | notch 2 |
NPY | neuropeptide Y |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 |
PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha |
PRSS23 | protease, serine, 23 |
RCN2 | reticulocalbin 2, EF-hand calcium binding domain |
RPS11 | ribosomal protein S11 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SACS | sacsin molecular chaperone |
SEPT11 | septin 11 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
SLK | STE20-like kinase |
SRP54 | signal recognition particle 54kDa |
STOM | stomatin |
TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TMEM2 | transmembrane protein 2 |
TSPAN3 | tetraspanin 3 |
UBE3C | ubiquitin protein ligase E3C |
VCAN | versican |