| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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242 genes differentially expressed following the BRD-K25737009_-666_A549_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACADVL | acyl-CoA dehydrogenase, very long chain |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ANKRD10 | ankyrin repeat domain 10 |
| ASS1 | argininosuccinate synthase 1 |
| ATF3 | activating transcription factor 3 |
| BAG3 | BCL2-associated athanogene 3 |
| BTG2 | BTG family, member 2 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CARKD | carbohydrate kinase domain containing |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CCNL1 | cyclin L1 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| COL9A2 | collagen, type IX, alpha 2 |
| CPE | carboxypeptidase E |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP8 | dual specificity phosphatase 8 |
| EGFL6 | EGF-like-domain, multiple 6 |
| EGR1 | early growth response 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAM46A | family with sequence similarity 46, member A |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FILIP1L | filamin A interacting protein 1-like |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GAS6 | growth arrest-specific 6 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GSDMB | gasdermin B |
| GUSBP11 | glucuronidase, beta pseudogene 11 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BG | histone cluster 1, H2bg |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IER5 | immediate early response 5 |
| IGHM | immunoglobulin heavy constant mu |
| IGKC | immunoglobulin kappa constant |
| IGL | immunoglobulin lambda locus |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| IL6 | interleukin 6 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| JUND | jun D proto-oncogene |
| KLF2 | Kruppel-like factor 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KLF6 | Kruppel-like factor 6 |
| L1CAM | L1 cell adhesion molecule |
| LDLR | low density lipoprotein receptor |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LOC100505650 | uncharacterized LOC100505650 |
| LOC399491 | |
| LUM | lumican |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MMP1 | matrix metallopeptidase 1 |
| MSLN | mesothelin |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OBSL1 | obscurin-like 1 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 |
| PLXNA1 | plexin A1 |
| PLXNB2 | plexin B2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POU2AF1 | POU class 2 associating factor 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS1 | regulator of G-protein signaling 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RGS2 | regulator of G-protein signaling 2 |
| RPL10 | ribosomal protein L10 |
| RRAD | Ras-related associated with diabetes |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SDC4 | syndecan 4 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SFTPB | surfactant protein B |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STC1 | stanniocalcin 1 |
| STX1A | syntaxin 1A (brain) |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TOP1 | topoisomerase (DNA) I |
| TRIB1 | tribbles pseudokinase 1 |
| TRIM36 | tripartite motif containing 36 |
| TSC22D1 | TSC22 domain family, member 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| VEGFA | vascular endothelial growth factor A |
| XIST | X inactive specific transcript (non-protein coding) |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ADD3 | adducin 3 (gamma) |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| AMD1 | adenosylmethionine decarboxylase 1 |
| ANXA7 | annexin A7 |
| ARF4 | ADP-ribosylation factor 4 |
| ATF1 | activating transcription factor 1 |
| ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) |
| B3GNT1 | |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BST2 | bone marrow stromal cell antigen 2 |
| BUB3 | BUB3 mitotic checkpoint protein |
| C6ORF120 | chromosome 6 open reading frame 120 |
| CALU | calumenin |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 |
| CCNA2 | cyclin A2 |
| CCNF | cyclin F |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC123 | cell division cycle 123 |
| CDCA4 | cell division cycle associated 4 |
| CHPT1 | choline phosphotransferase 1 |
| CIRBP | cold inducible RNA binding protein |
| COX11 | COX11 cytochrome c oxidase copper chaperone |
| CPD | carboxypeptidase D |
| CPNE3 | copine III |
| CTSB | cathepsin B |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DAZAP2 | DAZ associated protein 2 |
| DCK | deoxycytidine kinase |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DLD | dihydrolipoamide dehydrogenase |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| EAPP | E2F-associated phosphoprotein |
| ECI2 | enoyl-CoA delta isomerase 2 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EIF4E | eukaryotic translation initiation factor 4E |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| FASTKD5 | FAST kinase domains 5 |
| FBN2 | fibrillin 2 |
| FBXO3 | F-box protein 3 |
| FECH | ferrochelatase |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 |
| GCA | grancalcin, EF-hand calcium binding protein |
| GLTP | glycolipid transfer protein |
| GOLGA7 | golgin A7 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HAT1 | histone acetyltransferase 1 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
| HOXA10 | homeobox A10 |
| HOXC6 | homeobox C6 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IL6ST | interleukin 6 signal transducer |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| ITGA6 | integrin, alpha 6 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 |
| KIAA0391 | KIAA0391 |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LBR | lamin B receptor |
| LIPA | lipase A, lysosomal acid, cholesterol esterase |
| LYPLA1 | lysophospholipase I |
| MARCKSL1 | MARCKS-like 1 |
| MED21 | mediator complex subunit 21 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MPZL1 | myelin protein zero-like 1 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NAV3 | neuron navigator 3 |
| NPC2 | Niemann-Pick disease, type C2 |
| NPY | neuropeptide Y |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| OSBPL8 | oxysterol binding protein-like 8 |
| PDHX | pyruvate dehydrogenase complex, component X |
| PEX3 | peroxisomal biogenesis factor 3 |
| PLSCR4 | phospholipid scramblase 4 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 |
| RAB11A | RAB11A, member RAS oncogene family |
| RAB2A | RAB2A, member RAS oncogene family |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| RBP1 | retinol binding protein 1, cellular |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| REST | RE1-silencing transcription factor |
| RNF14 | ring finger protein 14 |
| RPA3 | replication protein A3, 14kDa |
| RPS11 | ribosomal protein S11 |
| SACS | sacsin molecular chaperone |
| SEC23A | Sec23 homolog A (S. cerevisiae) |
| SEH1L | SEH1-like (S. cerevisiae) |
| SELT | selenoprotein T |
| SKP1 | S-phase kinase-associated protein 1 |
| SORD | sorbitol dehydrogenase |
| SRP72 | signal recognition particle 72kDa |
| SSR1 | signal sequence receptor, alpha |
| STOM | stomatin |
| SUB1 | SUB1 homolog (S. cerevisiae) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TMEM168 | transmembrane protein 168 |
| TMEM185B | transmembrane protein 185B |
| TMX1 | thioredoxin-related transmembrane protein 1 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TOR1AIP1 | torsin A interacting protein 1 |
| TRAM1 | translocation associated membrane protein 1 |
| TRAPPC4 | trafficking protein particle complex 4 |
| TSPAN6 | tetraspanin 6 |
| TWF1 | twinfilin actin binding protein 1 |
| TXNDC9 | thioredoxin domain containing 9 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) |
| VAMP3 | vesicle-associated membrane protein 3 |
| VRK1 | vaccinia related kinase 1 |
| WWTR1 | WW domain containing transcription regulator 1 |
| YME1L1 | YME1-like 1 ATPase |
