Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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129 genes differentially expressed following the BRD-K25737009_-666_NCIH1694_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ALCAM | activated leukocyte cell adhesion molecule |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
ARMCX3 | armadillo repeat containing, X-linked 3 |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATF3 | activating transcription factor 3 |
CA2 | carbonic anhydrase II |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CEMIP | cell migration inducing protein, hyaluronan binding |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CLIC2 | chloride intracellular channel 2 |
COL15A1 | collagen, type XV, alpha 1 |
CTSG | cathepsin G |
DDIT4 | DNA-damage-inducible transcript 4 |
EREG | epiregulin |
GBP2 | guanylate binding protein 2, interferon-inducible |
GOLGA8A | golgin A8 family, member A |
GREM1 | gremlin 1, DAN family BMP antagonist |
GSTM3 | glutathione S-transferase mu 3 (brain) |
HAPLN1 | hyaluronan and proteoglycan link protein 1 |
HBB | hemoglobin, beta |
HIST1H2BG | histone cluster 1, H2bg |
IL6 | interleukin 6 |
KRT20 | keratin 20, type I |
LOX | lysyl oxidase |
MAP7 | microtubule-associated protein 7 |
MARS | methionyl-tRNA synthetase |
MMP12 | matrix metallopeptidase 12 |
MXRA5 | matrix-remodelling associated 5 |
NARFL | nuclear prelamin A recognition factor-like |
NPR3 | natriuretic peptide receptor 3 |
NRIP1 | nuclear receptor interacting protein 1 |
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
PHACTR2 | phosphatase and actin regulator 2 |
PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
RAB25 | RAB25, member RAS oncogene family |
RCAN1 | regulator of calcineurin 1 |
RGS1 | regulator of G-protein signaling 1 |
S100A14 | S100 calcium binding protein A14 |
S100A7 | S100 calcium binding protein A7 |
SATB2 | SATB homeobox 2 |
SH3YL1 | SH3 and SYLF domain containing 1 |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
SRGN | serglycin |
STAR | steroidogenic acute regulatory protein |
STC2 | stanniocalcin 2 |
SULF1 | sulfatase 1 |
TARS | threonyl-tRNA synthetase |
TCL1B | T-cell leukemia/lymphoma 1B |
TFF1 | trefoil factor 1 |
TFF3 | trefoil factor 3 (intestinal) |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TRIB3 | tribbles pseudokinase 3 |
TSC22D3 | TSC22 domain family, member 3 |
TXNIP | thioredoxin interacting protein |
XBP1 | X-box binding protein 1 |
Symbol | Name |
---|---|
ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
BAG5 | BCL2-associated athanogene 5 |
BCHE | butyrylcholinesterase |
C7 | complement component 7 |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
CANT1 | calcium activated nucleotidase 1 |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CDK19 | cyclin-dependent kinase 19 |
CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
CELF2 | CUGBP, Elav-like family member 2 |
CERK | ceramide kinase |
CHRDL1 | chordin-like 1 |
COPS7A | COP9 signalosome subunit 7A |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
DES | desmin |
EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
EIF5A | eukaryotic translation initiation factor 5A |
GNLY | granulysin |
GPX3 | glutathione peroxidase 3 |
GSTP1 | glutathione S-transferase pi 1 |
HIST1H2BD | histone cluster 1, H2bd |
HMGN3 | high mobility group nucleosomal binding domain 3 |
HN1 | hematological and neurological expressed 1 |
IFI44L | interferon-induced protein 44-like |
IGHM | immunoglobulin heavy constant mu |
IL13RA2 | interleukin 13 receptor, alpha 2 |
ISOC1 | isochorismatase domain containing 1 |
KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
KCTD12 | potassium channel tetramerization domain containing 12 |
KLRK1 | killer cell lectin-like receptor subfamily K, member 1 |
LAP3 | leucine aminopeptidase 3 |
LGALS1 | lectin, galactoside-binding, soluble, 1 |
LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
MSLN | mesothelin |
MTA1 | metastasis associated 1 |
NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
NREP | neuronal regeneration related protein |
NUP85 | nucleoporin 85kDa |
PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
PDLIM4 | PDZ and LIM domain 4 |
PEG10 | paternally expressed 10 |
PLBD1 | phospholipase B domain containing 1 |
PLN | phospholamban |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
PUF60 | poly-U binding splicing factor 60KDa |
RAB11FIP2 | RAB11 family interacting protein 2 (class I) |
RAI14 | retinoic acid induced 14 |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
RTN1 | reticulon 1 |
SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 |
SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
SPRY2 | sprouty homolog 2 (Drosophila) |
SRPX | sushi-repeat containing protein, X-linked |
STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
SVIL | supervillin |
TARBP1 | TAR (HIV-1) RNA binding protein 1 |
TBC1D31 | TBC1 domain family, member 31 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TRIB2 | tribbles pseudokinase 2 |
TSPAN7 | tetraspanin 7 |
UGDH | UDP-glucose 6-dehydrogenase |
WT1 | Wilms tumor 1 |
ZCCHC24 | zinc finger, CCHC domain containing 24 |
ZNF423 | zinc finger protein 423 |