BRD-K26241953_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-K26241953_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AMIGO2 adhesion molecule with Ig-like domain 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
CAV1 caveolin 1, caveolae protein, 22kDa
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
IER5 immediate early response 5
NR4A2 nuclear receptor subfamily 4, group A, member 2
PRSS2 protease, serine, 2 (trypsin 2)
SCCPDH saccharopine dehydrogenase (putative)
SDC1 syndecan 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A2 solute carrier family 38, member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
STS steroid sulfatase (microsomal), isozyme S
STX1A syntaxin 1A (brain)
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMPRSS3 transmembrane protease, serine 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TOX3 TOX high mobility group box family member 3
TPBG trophoblast glycoprotein
TXNIP thioredoxin interacting protein
WNT5A wingless-type MMTV integration site family, member 5A
ZBTB18 zinc finger and BTB domain containing 18
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
AQP4 aquaporin 4
BCHE butyrylcholinesterase
CD163 CD163 molecule
COCH cochlin
DLC1 DLC1 Rho GTPase activating protein
EPCAM epithelial cell adhesion molecule
GRWD1 glutamate-rich WD repeat containing 1
HMGB2 high mobility group box 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
LAMP3 lysosomal-associated membrane protein 3
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PMP2 peripheral myelin protein 2
RAB31 RAB31, member RAS oncogene family
RBP1 retinol binding protein 1, cellular
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SCG2 secretogranin II
SRPX sushi-repeat containing protein, X-linked
STK39 serine threonine kinase 39
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
Funding