BRD-K26241953_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K26241953_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
ACP5 acid phosphatase 5, tartrate resistant
AQP3 aquaporin 3 (Gill blood group)
CA12 carbonic anhydrase XII
CD300A CD300a molecule
CD58 CD58 molecule
CEP57 centrosomal protein 57kDa
CHGB chromogranin B
CLIC4 chloride intracellular channel 4
CLU clusterin
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP5 dual specificity phosphatase 5
FAM134A family with sequence similarity 134, member A
FAM134B family with sequence similarity 134, member B
FHL1 four and a half LIM domains 1
FXYD6 FXYD domain containing ion transport regulator 6
GLUL glutamate-ammonia ligase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HMOX1 heme oxygenase 1
HSPA2 heat shock 70kDa protein 2
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
INSIG1 insulin induced gene 1
KAZN kazrin, periplakin interacting protein
KIAA0125 KIAA0125
LDLR low density lipoprotein receptor
LTF lactotransferrin
MAP7 microtubule-associated protein 7
MAT2A methionine adenosyltransferase II, alpha
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP3 matrix metallopeptidase 3
MSMO1 methylsterol monooxygenase 1
NAMPT nicotinamide phosphoribosyltransferase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PIR pirin (iron-binding nuclear protein)
PPAP2B phosphatidic acid phosphatase type 2B
PRKCQ protein kinase C, theta
PROM1 prominin 1
PRUNE2 prune homolog 2 (Drosophila)
RNASE6 ribonuclease, RNase A family, k6
RNF167 ring finger protein 167
SCGB2A2 secretoglobin, family 2A, member 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TSKU tsukushi, small leucine rich proteoglycan
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VEGFA vascular endothelial growth factor A
VWA5A von Willebrand factor A domain containing 5A

decreased expression

Symbol Name
ALB albumin
APOB apolipoprotein B
CFI complement factor I
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
CYR61 cysteine-rich, angiogenic inducer, 61
H2AFV H2A histone family, member V
HCAR3 hydroxycarboxylic acid receptor 3
HEBP1 heme binding protein 1
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
KRT14 keratin 14, type I
KRT17 keratin 17, type I
MCUR1 mitochondrial calcium uniporter regulator 1
PEG10 paternally expressed 10
SMAD1 SMAD family member 1
TACSTD2 tumor-associated calcium signal transducer 2
TNS3 tensin 3