BRD-K26664453_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K26664453_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD36 CD36 molecule (thrombospondin receptor)
CLIC4 chloride intracellular channel 4
COL15A1 collagen, type XV, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
ERBB3 erb-b2 receptor tyrosine kinase 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV1 ets variant 1
FAM63A family with sequence similarity 63, member A
GEM GTP binding protein overexpressed in skeletal muscle
IGFBP3 insulin-like growth factor binding protein 3
INHBA inhibin, beta A
ITGB4 integrin, beta 4
MMP11 matrix metallopeptidase 11
MTA1 metastasis associated 1
MTMR11 myotubularin related protein 11
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NID1 nidogen 1
PNKP polynucleotide kinase 3'-phosphatase
RNF167 ring finger protein 167
STC1 stanniocalcin 1
STX1A syntaxin 1A (brain)
TMEM2 transmembrane protein 2
TP53 tumor protein p53
VCAN versican

decreased expression

Symbol Name
CCND1 cyclin D1
CD59 CD59 molecule, complement regulatory protein
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CKS2 CDC28 protein kinase regulatory subunit 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELOVL6 ELOVL fatty acid elongase 6
FABP6 fatty acid binding protein 6, ileal
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
PRSS23 protease, serine, 23
SRSF7 serine/arginine-rich splicing factor 7