BRD-K26669427_-666_MCF7_6.0_h_10.0_um Gene Set
Genes
47 genes differentially expressed following the BRD-K26669427_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
|
AKR1B10
|
aldo-keto reductase family 1, member B10 (aldose reductase)
|
|
AKR1C1
|
aldo-keto reductase family 1, member C1
|
|
AKR1C2
|
aldo-keto reductase family 1, member C2
|
|
ARG2
|
arginase 2
|
|
C10ORF10
|
chromosome 10 open reading frame 10
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
|
CLIC2
|
chloride intracellular channel 2
|
|
EPHX1
|
epoxide hydrolase 1, microsomal (xenobiotic)
|
|
GCLM
|
glutamate-cysteine ligase, modifier subunit
|
|
HMOX1
|
heme oxygenase 1
|
|
HSPA6
|
heat shock 70kDa protein 6 (HSP70B')
|
|
MDFIC
|
MyoD family inhibitor domain containing
|
|
N4BP2L1
|
NEDD4 binding protein 2-like 1
|
|
NQO1
|
NAD(P)H dehydrogenase, quinone 1
|
|
NXN
|
nucleoredoxin
|
|
RNASE1
|
ribonuclease, RNase A family, 1 (pancreatic)
|
|
SLC7A11
|
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
|
|
SQSTM1
|
sequestosome 1
|
|
TDO2
|
tryptophan 2,3-dioxygenase
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
|
TRIB3
|
tribbles pseudokinase 3
|
|
TXNRD1
|
thioredoxin reductase 1
|
|
UCHL1
|
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
|
decreased expression
| Symbol |
Name |
|
ACTA2
|
actin, alpha 2, smooth muscle, aorta
|
|
CDC42
|
cell division cycle 42
|
|
CXCL12
|
chemokine (C-X-C motif) ligand 12
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
|
DKK1
|
dickkopf WNT signaling pathway inhibitor 1
|
|
EIF5B
|
eukaryotic translation initiation factor 5B
|
|
LUC7L3
|
LUC7-like 3 (S. cerevisiae)
|
|
LYZ
|
lysozyme
|
|
MMP9
|
matrix metallopeptidase 9
|
|
MRPL19
|
mitochondrial ribosomal protein L19
|
|
PITX1
|
paired-like homeodomain 1
|
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta
|
|
PRSS3
|
protease, serine, 3
|
|
PTCH1
|
patched 1
|
|
REG1A
|
regenerating islet-derived 1 alpha
|
|
RGS4
|
regulator of G-protein signaling 4
|
|
S100P
|
S100 calcium binding protein P
|
|
SCG2
|
secretogranin II
|
|
SOX9
|
SRY (sex determining region Y)-box 9
|
|
SRSF6
|
serine/arginine-rich splicing factor 6
|
|
TCN1
|
transcobalamin I (vitamin B12 binding protein, R binder family)
|
|
TFAP2B
|
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
|
