BRD-K26760349_HG-9-91-01_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K26760349_HG-9-91-01_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARG1 arginase 1
BSG basigin (Ok blood group)
C7 complement component 7
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD69 CD69 molecule
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL2 chemokine (C-X-C motif) ligand 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMD dystrophin
DSP desmoplakin
EFHC2 EF-hand domain (C-terminal) containing 2
EPCAM epithelial cell adhesion molecule
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM129A family with sequence similarity 129, member A
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAL histidine ammonia-lyase
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IL1R2 interleukin 1 receptor, type II
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAPTM4B lysosomal protein transmembrane 4 beta
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MOXD1 monooxygenase, DBH-like 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
PPAP2B phosphatidic acid phosphatase type 2B
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RGS2 regulator of G-protein signaling 2
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SEPP1 selenoprotein P, plasma, 1
SGK1 serum/glucocorticoid regulated kinase 1
SPTSSA serine palmitoyltransferase, small subunit A
STK26 serine/threonine protein kinase 26
TF transferrin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TYRP1 tyrosinase-related protein 1

decreased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
BTG2 BTG family, member 2
CCND2 cyclin D2
CDC20 cell division cycle 20
CNN3 calponin 3, acidic
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
EPHB2 EPH receptor B2
FADS1 fatty acid desaturase 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GALC galactosylceramidase
GPATCH8 G patch domain containing 8
GPRC5A G protein-coupled receptor, class C, group 5, member A
HMOX1 heme oxygenase 1
KIF20A kinesin family member 20A
KRT19 keratin 19, type I
LGALS1 lectin, galactoside-binding, soluble, 1
MT1M metallothionein 1M
NEFH neurofilament, heavy polypeptide
NR2F2 nuclear receptor subfamily 2, group F, member 2
RHOBTB3 Rho-related BTB domain containing 3
RND3 Rho family GTPase 3
RNH1 ribonuclease/angiogenin inhibitor 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SH3BGRL SH3 domain binding glutamate-rich protein like
TCF4 transcription factor 4
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRIM22 tripartite motif containing 22
TRIP6 thyroid hormone receptor interactor 6
ZNF586 zinc finger protein 586
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