BRD-K26822808_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-K26822808_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
BASP1 brain abundant, membrane attached signal protein 1
BLVRB biliverdin reductase B
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD36 CD36 molecule (thrombospondin receptor)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL7A1 collagen, type VII, alpha 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
DUSP5 dual specificity phosphatase 5
F3 coagulation factor III (thromboplastin, tissue factor)
GBP1 guanylate binding protein 1, interferon-inducible
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HRH1 histamine receptor H1
IQCG IQ motif containing G
KLK10 kallikrein-related peptidase 10
NAMPT nicotinamide phosphoribosyltransferase
NPR3 natriuretic peptide receptor 3
PAEP progestagen-associated endometrial protein
PI3 peptidase inhibitor 3, skin-derived
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TGM2 transglutaminase 2
TMEM158 transmembrane protein 158 (gene/pseudogene)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AHR aryl hydrocarbon receptor
ALB albumin
ANXA3 annexin A3
CRABP1 cellular retinoic acid binding protein 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GOLGA8H golgin A8 family, member H
IGL immunoglobulin lambda locus
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
PPARG peroxisome proliferator-activated receptor gamma
RGS5 regulator of G-protein signaling 5
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SYBU syntabulin (syntaxin-interacting)
TSPAN8 tetraspanin 8