BRD-K26838195_AST1306_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K26838195_AST1306_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CFB complement factor B
COL11A1 collagen, type XI, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A5 collagen, type IV, alpha 5
COL5A2 collagen, type V, alpha 2
CREG1 cellular repressor of E1A-stimulated genes 1
CRELD2 cysteine-rich with EGF-like domains 2
CXCL14 chemokine (C-X-C motif) ligand 14
EDNRA endothelin receptor type A
FAM129A family with sequence similarity 129, member A
FBLN1 fibulin 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
H1FX H1 histone family, member X
HDAC1 histone deacetylase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
KLF10 Kruppel-like factor 10
KRT17 keratin 17, type I
METTL7A methyltransferase like 7A
NBL1 neuroblastoma 1, DAN family BMP antagonist
NELL2 NEL-like 2 (chicken)
NMRK1 nicotinamide riboside kinase 1
PCOLCE procollagen C-endopeptidase enhancer
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
TATDN2 TatD DNase domain containing 2
TMSB15A thymosin beta 15a
TPSAB1 tryptase alpha/beta 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATF5 activating transcription factor 5
CA12 carbonic anhydrase XII
CD9 CD9 molecule
CREB1 cAMP responsive element binding protein 1
CTSG cathepsin G
CYBB cytochrome b-245, beta polypeptide
DMXL2 Dmx-like 2
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5 eukaryotic translation initiation factor 5
FABP4 fatty acid binding protein 4, adipocyte
FOLR1 folate receptor 1 (adult)
HDDC2 HD domain containing 2
HLX H2.0-like homeobox
HOXB2 homeobox B2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KANK1 KN motif and ankyrin repeat domains 1
KRT7 keratin 7, type II
MFAP5 microfibrillar associated protein 5
MINA MYC induced nuclear antigen
MOK MOK protein kinase
N4BP2L2 NEDD4 binding protein 2-like 2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
Funding