Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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69 genes differentially expressed following the BRD-K27630941_N-(2-methoxyphenyl)-4-morpholino-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-amine hw-gc-act01_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACLY | ATP citrate lyase |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AMDHD2 | amidohydrolase domain containing 2 |
APOD | apolipoprotein D |
CD24 | CD24 molecule |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CLGN | calmegin |
CRISP3 | cysteine-rich secretory protein 3 |
CXADR | coxsackie virus and adenovirus receptor |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
CYTL1 | cytokine-like 1 |
DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 |
DSG2 | desmoglein 2 |
EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
FABP7 | fatty acid binding protein 7, brain |
FCHO1 | FCH domain only 1 |
GRB10 | growth factor receptor-bound protein 10 |
HMOX1 | heme oxygenase 1 |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
IGLL1 | immunoglobulin lambda-like polypeptide 1 |
KRT14 | keratin 14, type I |
KRT16 | keratin 16, type I |
LAPTM4B | lysosomal protein transmembrane 4 beta |
LDOC1 | leucine zipper, down-regulated in cancer 1 |
MSMO1 | methylsterol monooxygenase 1 |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SQSTM1 | sequestosome 1 |
TPD52 | tumor protein D52 |
VCAM1 | vascular cell adhesion molecule 1 |
Symbol | Name |
---|---|
BPHL | biphenyl hydrolase-like (serine hydrolase) |
CD46 | CD46 molecule, complement regulatory protein |
COL1A2 | collagen, type I, alpha 2 |
COL5A2 | collagen, type V, alpha 2 |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DCN | decorin |
DHFR | dihydrofolate reductase |
DMD | dystrophin |
DUSP6 | dual specificity phosphatase 6 |
EMP1 | epithelial membrane protein 1 |
FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
HBB | hemoglobin, beta |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
KIAA0101 | KIAA0101 |
METTL7A | methyltransferase like 7A |
NID1 | nidogen 1 |
OBSL1 | obscurin-like 1 |
POSTN | periostin, osteoblast specific factor |
PRAME | preferentially expressed antigen in melanoma |
PTK2 | protein tyrosine kinase 2 |
RBPMS | RNA binding protein with multiple splicing |
REEP1 | receptor accessory protein 1 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
THBS1 | thrombospondin 1 |
TIMP1 | TIMP metallopeptidase inhibitor 1 |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TUBB6 | tubulin, beta 6 class V |
TXNIP | thioredoxin interacting protein |
VCAN | versican |
WFDC2 | WAP four-disulfide core domain 2 |
ZNF652 | zinc finger protein 652 |