BRD-K28120222_Prestw-550_PC3_6.0_h_10.0_um Gene Set
Genes
53 genes differentially expressed following the BRD-K28120222_Prestw-550_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
AKR1C1
|
aldo-keto reductase family 1, member C1
|
|
AKR1C2
|
aldo-keto reductase family 1, member C2
|
|
AKR1C3
|
aldo-keto reductase family 1, member C3
|
|
CYP1B1
|
cytochrome P450, family 1, subfamily B, polypeptide 1
|
|
DNAJB4
|
DnaJ (Hsp40) homolog, subfamily B, member 4
|
|
FOLR1
|
folate receptor 1 (adult)
|
|
FTH1
|
ferritin, heavy polypeptide 1
|
|
GAB2
|
GRB2-associated binding protein 2
|
|
GCLM
|
glutamate-cysteine ligase, modifier subunit
|
|
GLA
|
galactosidase, alpha
|
|
HMOX1
|
heme oxygenase 1
|
|
HOMER2
|
homer scaffolding protein 2
|
|
HSPA6
|
heat shock 70kDa protein 6 (HSP70B')
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
|
LHFPL2
|
lipoma HMGIC fusion partner-like 2
|
|
MAFB
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
|
|
NELL2
|
NEL-like 2 (chicken)
|
|
PPBP
|
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
|
|
RORA
|
RAR-related orphan receptor A
|
|
SCGB2A1
|
secretoglobin, family 2A, member 1
|
|
SFN
|
stratifin
|
|
SLC7A11
|
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
|
|
SLPI
|
secretory leukocyte peptidase inhibitor
|
|
TXNRD1
|
thioredoxin reductase 1
|
decreased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta
|
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide
|
|
CCL18
|
chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
|
|
DUSP4
|
dual specificity phosphatase 4
|
|
FABP4
|
fatty acid binding protein 4, adipocyte
|
|
FBLN1
|
fibulin 1
|
|
FERMT1
|
fermitin family member 1
|
|
FHL1
|
four and a half LIM domains 1
|
|
G0S2
|
G0/G1 switch 2
|
|
HOXA10
|
homeobox A10
|
|
HOXA11
|
homeobox A11
|
|
HOXA5
|
homeobox A5
|
|
IGFBP7
|
insulin-like growth factor binding protein 7
|
|
IL1B
|
interleukin 1, beta
|
|
KRT18
|
keratin 18, type I
|
|
LAMB1
|
laminin, beta 1
|
|
NFIB
|
nuclear factor I/B
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
|
OLFM4
|
olfactomedin 4
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
|
RGS5
|
regulator of G-protein signaling 5
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
|
SOX4
|
SRY (sex determining region Y)-box 4
|
|
SPDEF
|
SAM pointed domain containing ETS transcription factor
|
|
SRPX
|
sushi-repeat containing protein, X-linked
|
|
TWIST1
|
twist family bHLH transcription factor 1
|
|
VIM
|
vimentin
|
