Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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86 genes differentially expressed following the BRD-K28143534_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
C4BPA | complement component 4 binding protein, alpha |
CES1 | carboxylesterase 1 |
CHI3L2 | chitinase 3-like 2 |
CLC | Charcot-Leyden crystal galectin |
CLU | clusterin |
CRISP3 | cysteine-rich secretory protein 3 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DLK1 | delta-like 1 homolog (Drosophila) |
FOSL1 | FOS-like antigen 1 |
FOXO3 | forkhead box O3 |
HHEX | hematopoietically expressed homeobox |
HP | haptoglobin |
IER3 | immediate early response 3 |
IGFBP4 | insulin-like growth factor binding protein 4 |
IGL | immunoglobulin lambda locus |
JUN | jun proto-oncogene |
KLF6 | Kruppel-like factor 6 |
KRT18 | keratin 18, type I |
LTF | lactotransferrin |
MCL1 | myeloid cell leukemia 1 |
MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
MSX1 | msh homeobox 1 |
NELL2 | NEL-like 2 (chicken) |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
ORM1 | orosomucoid 1 |
PEG3 | paternally expressed 3 |
PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
RHOB | ras homolog family member B |
S100P | S100 calcium binding protein P |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SMYD3 | SET and MYND domain containing 3 |
SOX4 | SRY (sex determining region Y)-box 4 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
TXNL4B | thioredoxin-like 4B |
WNT5A | wingless-type MMTV integration site family, member 5A |
XIST | X inactive specific transcript (non-protein coding) |
ZBTB20 | zinc finger and BTB domain containing 20 |
ZNF586 | zinc finger protein 586 |
Symbol | Name |
---|---|
ABHD2 | abhydrolase domain containing 2 |
ACTA2 | actin, alpha 2, smooth muscle, aorta |
ADI1 | acireductone dioxygenase 1 |
ADIRF | adipogenesis regulatory factor |
AGTR1 | angiotensin II receptor, type 1 |
AQP3 | aquaporin 3 (Gill blood group) |
C6ORF62 | chromosome 6 open reading frame 62 |
CANT1 | calcium activated nucleotidase 1 |
CCNB2 | cyclin B2 |
CCNG2 | cyclin G2 |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CPB1 | carboxypeptidase B1 (tissue) |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DCK | deoxycytidine kinase |
DPYSL2 | dihydropyrimidinase-like 2 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
GJA1 | gap junction protein, alpha 1, 43kDa |
GOLT1B | golgi transport 1B |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
HSPA1A | heat shock 70kDa protein 1A |
INSIG1 | insulin induced gene 1 |
KCTD12 | potassium channel tetramerization domain containing 12 |
KRT14 | keratin 14, type I |
LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
LYPLA1 | lysophospholipase I |
MYH11 | myosin, heavy chain 11, smooth muscle |
NOV | nephroblastoma overexpressed |
NT5DC2 | 5'-nucleotidase domain containing 2 |
OLFM4 | olfactomedin 4 |
PBK | PDZ binding kinase |
PCNA | proliferating cell nuclear antigen |
PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
RNASE4 | ribonuclease, RNase A family, 4 |
SNN | stannin |
TAGLN | transgelin |
TIGAR | TP53 induced glycolysis regulatory phosphatase |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
TM4SF1 | transmembrane 4 L six family member 1 |