Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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106 genes differentially expressed following the BRD-K28453807_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ALDOB | aldolase B, fructose-bisphosphate |
ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
ANXA4 | annexin A4 |
ARL4C | ADP-ribosylation factor-like 4C |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
CASP3 | caspase 3, apoptosis-related cysteine peptidase |
CD24 | CD24 molecule |
CD44 | CD44 molecule (Indian blood group) |
CD9 | CD9 molecule |
CKLF | chemokine-like factor |
CLC | Charcot-Leyden crystal galectin |
COL1A2 | collagen, type I, alpha 2 |
CPA3 | carboxypeptidase A3 (mast cell) |
CRIP2 | cysteine-rich protein 2 |
CRISP3 | cysteine-rich secretory protein 3 |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
DPYD | dihydropyrimidine dehydrogenase |
EVI2A | ecotropic viral integration site 2A |
EZR | ezrin |
FGFR3 | fibroblast growth factor receptor 3 |
GJA1 | gap junction protein, alpha 1, 43kDa |
GPNMB | glycoprotein (transmembrane) nmb |
GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
IL17RB | interleukin 17 receptor B |
KRT23 | keratin 23, type I |
LPAR6 | lysophosphatidic acid receptor 6 |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MMP9 | matrix metallopeptidase 9 |
MTSS1 | metastasis suppressor 1 |
MXRA5 | matrix-remodelling associated 5 |
MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PDLIM3 | PDZ and LIM domain 3 |
PDZK1IP1 | PDZK1 interacting protein 1 |
PEG10 | paternally expressed 10 |
PLIN2 | perilipin 2 |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
RGS1 | regulator of G-protein signaling 1 |
RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SDC2 | syndecan 2 |
SNX7 | sorting nexin 7 |
SPON2 | spondin 2, extracellular matrix protein |
SST | somatostatin |
SULF1 | sulfatase 1 |
TCF4 | transcription factor 4 |
TOX | thymocyte selection-associated high mobility group box |
TPD52 | tumor protein D52 |
TRDV3 | T cell receptor delta variable 3 |
VEGFA | vascular endothelial growth factor A |
WT1 | Wilms tumor 1 |
XIST | X inactive specific transcript (non-protein coding) |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
ZIC1 | Zic family member 1 |
Symbol | Name |
---|---|
ADI1 | acireductone dioxygenase 1 |
AGR2 | anterior gradient 2 |
ALCAM | activated leukocyte cell adhesion molecule |
ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
APOD | apolipoprotein D |
ASCL1 | achaete-scute family bHLH transcription factor 1 |
C2CD2 | C2 calcium-dependent domain containing 2 |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CST3 | cystatin C |
CSTA | cystatin A (stefin A) |
CXCL5 | chemokine (C-X-C motif) ligand 5 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
EBP | emopamil binding protein (sterol isomerase) |
FAM13A | family with sequence similarity 13, member A |
GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
GDF15 | growth differentiation factor 15 |
GMDS | GDP-mannose 4,6-dehydratase |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
GRN | granulin |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LIG1 | ligase I, DNA, ATP-dependent |
LTBP3 | latent transforming growth factor beta binding protein 3 |
MCOLN1 | mucolipin 1 |
NPY1R | neuropeptide Y receptor Y1 |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
OXTR | oxytocin receptor |
PTGES | prostaglandin E synthase |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SIDT2 | SID1 transmembrane family, member 2 |
SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 |
SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
SOX4 | SRY (sex determining region Y)-box 4 |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
SRPX | sushi-repeat containing protein, X-linked |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFF1 | trefoil factor 1 |
TFF3 | trefoil factor 3 (intestinal) |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TNC | tenascin C |
TSPAN8 | tetraspanin 8 |
VCAN | versican |