BRD-K28610502_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-K28610502_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CCL20 chemokine (C-C motif) ligand 20
CD36 CD36 molecule (thrombospondin receptor)
DUSP5 dual specificity phosphatase 5
EGR3 early growth response 3
EPCAM epithelial cell adhesion molecule
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
IER3 immediate early response 3
KLF4 Kruppel-like factor 4 (gut)
KLF9 Kruppel-like factor 9
LDLR low density lipoprotein receptor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MGLL monoglyceride lipase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLIN2 perilipin 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTX3 pentraxin 3, long
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPM4 tropomyosin 4
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ASMTL acetylserotonin O-methyltransferase-like
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNB2 ephrin-B2
ITM2A integral membrane protein 2A
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4