Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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106 genes differentially expressed following the BRD-K29395450_PIK-93_BT20_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABHD4 | abhydrolase domain containing 4 |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
ARHGAP32 | Rho GTPase activating protein 32 |
BACE2 | beta-site APP-cleaving enzyme 2 |
BEX1 | brain expressed, X-linked 1 |
CDK19 | cyclin-dependent kinase 19 |
CEMIP | cell migration inducing protein, hyaluronan binding |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
ERAP2 | endoplasmic reticulum aminopeptidase 2 |
ERBB3 | erb-b2 receptor tyrosine kinase 3 |
FHL1 | four and a half LIM domains 1 |
FLRT2 | fibronectin leucine rich transmembrane protein 2 |
GBP2 | guanylate binding protein 2, interferon-inducible |
H1F0 | H1 histone family, member 0 |
HBP1 | HMG-box transcription factor 1 |
HIST1H2AC | histone cluster 1, H2ac |
HIST1H2BD | histone cluster 1, H2bd |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
IGFBP5 | insulin-like growth factor binding protein 5 |
IRS2 | insulin receptor substrate 2 |
KDM3A | lysine (K)-specific demethylase 3A |
LMO2 | LIM domain only 2 (rhombotin-like 1) |
METTL7A | methyltransferase like 7A |
MTSS1 | metastasis suppressor 1 |
NBR1 | neighbor of BRCA1 gene 1 |
PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
PLSCR4 | phospholipid scramblase 4 |
PRKCH | protein kinase C, eta |
PTGES | prostaglandin E synthase |
RALGDS | ral guanine nucleotide dissociation stimulator |
RB1CC1 | RB1-inducible coiled-coil 1 |
REEP1 | receptor accessory protein 1 |
RGS5 | regulator of G-protein signaling 5 |
RTN2 | reticulon 2 |
SCG5 | secretogranin V |
SEPP1 | selenoprotein P, plasma, 1 |
SLC38A2 | solute carrier family 38, member 2 |
SOX4 | SRY (sex determining region Y)-box 4 |
SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
SRPX | sushi-repeat containing protein, X-linked |
STOM | stomatin |
TNS1 | tensin 1 |
TPP1 | tripeptidyl peptidase I |
TSC22D3 | TSC22 domain family, member 3 |
TSPAN8 | tetraspanin 8 |
TXNIP | thioredoxin interacting protein |
YPEL5 | yippee-like 5 (Drosophila) |
Symbol | Name |
---|---|
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
CD24 | CD24 molecule |
CDC6 | cell division cycle 6 |
CSE1L | CSE1 chromosome segregation 1-like (yeast) |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
DEFB1 | defensin, beta 1 |
EIF5A | eukaryotic translation initiation factor 5A |
ENO1 | enolase 1, (alpha) |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FEN1 | flap structure-specific endonuclease 1 |
FGFR2 | fibroblast growth factor receptor 2 |
FOSL1 | FOS-like antigen 1 |
GINS2 | GINS complex subunit 2 (Psf2 homolog) |
GPI | glucose-6-phosphate isomerase |
HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
HSPA8 | heat shock 70kDa protein 8 |
HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
KAZN | kazrin, periplakin interacting protein |
KRT18 | keratin 18, type I |
KRT6B | keratin 6B, type II |
LIG1 | ligase I, DNA, ATP-dependent |
MCM10 | minichromosome maintenance complex component 10 |
MCM3 | minichromosome maintenance complex component 3 |
MCM6 | minichromosome maintenance complex component 6 |
MCM7 | minichromosome maintenance complex component 7 |
MRPL12 | mitochondrial ribosomal protein L12 |
MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
PEG3 | paternally expressed 3 |
PFKP | phosphofructokinase, platelet |
PFN2 | profilin 2 |
PGK1 | phosphoglycerate kinase 1 |
PGM1 | phosphoglucomutase 1 |
PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
PNP | purine nucleoside phosphorylase |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
RANBP1 | RAN binding protein 1 |
RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
RRM1 | ribonucleotide reductase M1 |
S100A9 | S100 calcium binding protein A9 |
SEPT9 | septin 9 |
SFN | stratifin |
SLC43A3 | solute carrier family 43, member 3 |
TAGLN2 | transgelin 2 |
TFRC | transferrin receptor |
TM4SF1 | transmembrane 4 L six family member 1 |
TPM1 | tropomyosin 1 (alpha) |
TUBB | tubulin, beta class I |
TYMS | thymidylate synthetase |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |