BRD-K29395450_PIK-93_HS578T_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-K29395450_PIK-93_HS578T_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADD3 adducin 3 (gamma)
ADIRF adipogenesis regulatory factor
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C6ORF48 chromosome 6 open reading frame 48
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CRISP3 cysteine-rich secretory protein 3
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
EPHA3 EPH receptor A3
GADD45B growth arrest and DNA-damage-inducible, beta
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GOLGA8H golgin A8 family, member H
IFRD2 interferon-related developmental regulator 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
LDB2 LIM domain binding 2
LOC100272216 uncharacterized LOC100272216
LPAR1 lysophosphatidic acid receptor 1
LRMP lymphoid-restricted membrane protein
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PILRB paired immunoglobin-like type 2 receptor beta
PLAGL1 pleiomorphic adenoma gene-like 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
STX1A syntaxin 1A (brain)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNC tenascin C
TRA2A transformer 2 alpha homolog (Drosophila)

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
DDIT4 DNA-damage-inducible transcript 4
DRAM1 DNA-damage regulated autophagy modulator 1
DUSP14 dual specificity phosphatase 14
FGFR2 fibroblast growth factor receptor 2
LAPTM4B lysosomal protein transmembrane 4 beta
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX3-1 NK3 homeobox 1
P3H2 prolyl 3-hydroxylase 2
PCNA proliferating cell nuclear antigen
PNP purine nucleoside phosphorylase
SESN1 sestrin 1
SQLE squalene epoxidase
VCAN versican
Funding