| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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147 genes differentially expressed following the BRD-K29395450_PIK-93_HT29_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANGPT1 | angiopoietin 1 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ASS1 | argininosuccinate synthase 1 |
| ATF4 | activating transcription factor 4 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| ATP9A | ATPase, class II, type 9A |
| AZIN1 | antizyme inhibitor 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CD47 | CD47 molecule |
| CTSB | cathepsin B |
| CXADR | coxsackie virus and adenovirus receptor |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| EDN1 | endothelin 1 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOXO4 | forkhead box O4 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GOLGA8A | golgin A8 family, member A |
| HLA-E | major histocompatibility complex, class I, E |
| IFI44L | interferon-induced protein 44-like |
| IRS2 | insulin receptor substrate 2 |
| ITM2A | integral membrane protein 2A |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KRT7 | keratin 7, type II |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LOC100505650 | uncharacterized LOC100505650 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MEIS1 | Meis homeobox 1 |
| MLPH | melanophilin |
| MVP | major vault protein |
| NEBL | nebulette |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NRCAM | neuronal cell adhesion molecule |
| PLSCR4 | phospholipid scramblase 4 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PSAP | prosaposin |
| PTPRK | protein tyrosine phosphatase, receptor type, K |
| RAB4A | RAB4A, member RAS oncogene family |
| RAP1GAP | RAP1 GTPase activating protein |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 |
| REEP1 | receptor accessory protein 1 |
| RPL37A | ribosomal protein L37a |
| RPL38 | ribosomal protein L38 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RSRP1 | arginine/serine-rich protein 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STMN2 | stathmin 2 |
| STX1A | syntaxin 1A (brain) |
| SYT1 | synaptotagmin I |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRIM2 | tripartite motif containing 2 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPO | translocator protein (18kDa) |
| UFM1 | ubiquitin-fold modifier 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| ACP5 | acid phosphatase 5, tartrate resistant |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| AURKA | aurora kinase A |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CCNF | cyclin F |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CDCA3 | cell division cycle associated 3 |
| CDK1 | cyclin-dependent kinase 1 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CENPE | centromere protein E, 312kDa |
| CENPN | centromere protein N |
| CENPU | centromere protein U |
| CIT | citron rho-interacting serine/threonine kinase |
| COL1A1 | collagen, type I, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| CTSV | cathepsin V |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DBF4 | DBF4 zinc finger |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| FAM129A | family with sequence similarity 129, member A |
| FEN1 | flap structure-specific endonuclease 1 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FPGS | folylpolyglutamate synthase |
| FXYD6 | FXYD domain containing ion transport regulator 6 |
| FZD5 | frizzled class receptor 5 |
| GAL | galanin/GMAP prepropeptide |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GSTA1 | glutathione S-transferase alpha 1 |
| H2AFX | H2A histone family, member X |
| HBB | hemoglobin, beta |
| HMGB2 | high mobility group box 2 |
| HMGB3 | high mobility group box 3 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM6 | minichromosome maintenance complex component 6 |
| MKI67 | marker of proliferation Ki-67 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MMP9 | matrix metallopeptidase 9 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDC80 | NDC80 kinetochore complex component |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NEK2 | NIMA-related kinase 2 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NMU | neuromedin U |
| OIP5 | Opa interacting protein 5 |
| OLFML2B | olfactomedin-like 2B |
| PBK | PDZ binding kinase |
| PLK1 | polo-like kinase 1 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| RRM2 | ribonucleotide reductase M2 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
| SPAG5 | sperm associated antigen 5 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SRGN | serglycin |
| STAR | steroidogenic acute regulatory protein |
| TDO2 | tryptophan 2,3-dioxygenase |
| TK1 | thymidine kinase 1, soluble |
| TMPO | thymopoietin |
| TPX2 | TPX2, microtubule-associated |
| TUBB2A | tubulin, beta 2A class IIa |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| VRK1 | vaccinia related kinase 1 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| ZWINT | ZW10 interacting kinetochore protein |
