Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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140 genes differentially expressed following the BRD-K29415052_NVP-BGT226_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
ABHD2 | abhydrolase domain containing 2 |
ABHD4 | abhydrolase domain containing 4 |
AGTR1 | angiotensin II receptor, type 1 |
ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
ANXA10 | annexin A10 |
APOD | apolipoprotein D |
APOE | apolipoprotein E |
ARHGAP29 | Rho GTPase activating protein 29 |
ASPN | asporin |
BGN | biglycan |
BHLHE41 | basic helix-loop-helix family, member e41 |
C10ORF10 | chromosome 10 open reading frame 10 |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CD59 | CD59 molecule, complement regulatory protein |
CD9 | CD9 molecule |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CLEC2B | C-type lectin domain family 2, member B |
CST1 | cystatin SN |
DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
DUSP6 | dual specificity phosphatase 6 |
ERBB3 | erb-b2 receptor tyrosine kinase 3 |
F12 | coagulation factor XII (Hageman factor) |
F5 | coagulation factor V (proaccelerin, labile factor) |
FABP4 | fatty acid binding protein 4, adipocyte |
FHL2 | four and a half LIM domains 2 |
FOXO4 | forkhead box O4 |
FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
GIMAP4 | GTPase, IMAP family member 4 |
GLRX | glutaredoxin (thioltransferase) |
HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
HSPG2 | heparan sulfate proteoglycan 2 |
INPP1 | inositol polyphosphate-1-phosphatase |
ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
ITGA6 | integrin, alpha 6 |
ITGB5 | integrin, beta 5 |
LCN2 | lipocalin 2 |
LIMA1 | LIM domain and actin binding 1 |
LRP10 | low density lipoprotein receptor-related protein 10 |
LY6E | lymphocyte antigen 6 complex, locus E |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAP1B | microtubule-associated protein 1B |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MMP7 | matrix metallopeptidase 7 |
MTA1 | metastasis associated 1 |
MVP | major vault protein |
MYO6 | myosin VI |
NOS3 | nitric oxide synthase 3 (endothelial cell) |
NT5E | 5'-nucleotidase, ecto (CD73) |
PDZK1IP1 | PDZK1 interacting protein 1 |
PIP | prolactin-induced protein |
PLA1A | phospholipase A1 member A |
PPAP2C | phosphatidic acid phosphatase type 2C |
RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
RGS5 | regulator of G-protein signaling 5 |
SEC14L1 | SEC14-like 1 (S. cerevisiae) |
SOX9 | SRY (sex determining region Y)-box 9 |
SQSTM1 | sequestosome 1 |
SRGN | serglycin |
SRPX | sushi-repeat containing protein, X-linked |
SSFA2 | sperm specific antigen 2 |
SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
TBC1D4 | TBC1 domain family, member 4 |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
THBS2 | thrombospondin 2 |
TLR4 | toll-like receptor 4 |
TM4SF1 | transmembrane 4 L six family member 1 |
TMC5 | transmembrane channel-like 5 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TSPAN4 | tetraspanin 4 |
TSPAN8 | tetraspanin 8 |
VNN1 | vanin 1 |
ZBTB16 | zinc finger and BTB domain containing 16 |
Symbol | Name |
---|---|
ACKR3 | atypical chemokine receptor 3 |
ADIRF | adipogenesis regulatory factor |
ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
BIRC5 | baculoviral IAP repeat containing 5 |
CCNA2 | cyclin A2 |
CCNB2 | cyclin B2 |
CDC20 | cell division cycle 20 |
CDC25A | cell division cycle 25A |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CENPA | centromere protein A |
CENPF | centromere protein F, 350/400kDa |
CENPU | centromere protein U |
CIT | citron rho-interacting serine/threonine kinase |
CLIC3 | chloride intracellular channel 3 |
CLU | clusterin |
CSRP2 | cysteine and glycine-rich protein 2 |
DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FEN1 | flap structure-specific endonuclease 1 |
FOLR1 | folate receptor 1 (adult) |
GINS2 | GINS complex subunit 2 (Psf2 homolog) |
GPM6B | glycoprotein M6B |
H2AFV | H2A histone family, member V |
H2AFX | H2A histone family, member X |
HILPDA | hypoxia inducible lipid droplet-associated |
HIST1H2BG | histone cluster 1, H2bg |
HMGB2 | high mobility group box 2 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
IGL | immunoglobulin lambda locus |
IL1R1 | interleukin 1 receptor, type I |
KIF20A | kinesin family member 20A |
MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
MAL | mal, T-cell differentiation protein |
MELK | maternal embryonic leucine zipper kinase |
NEK2 | NIMA-related kinase 2 |
NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
NREP | neuronal regeneration related protein |
P3H2 | prolyl 3-hydroxylase 2 |
PBK | PDZ binding kinase |
PCP4 | Purkinje cell protein 4 |
PENK | proenkephalin |
PGAM1 | phosphoglycerate mutase 1 (brain) |
PLK1 | polo-like kinase 1 |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PRC1 | protein regulator of cytokinesis 1 |
PRDX2 | peroxiredoxin 2 |
PTTG1 | pituitary tumor-transforming 1 |
RRM2 | ribonucleotide reductase M2 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SFN | stratifin |
SMC4 | structural maintenance of chromosomes 4 |
SQLE | squalene epoxidase |
STMN1 | stathmin 1 |
TK1 | thymidine kinase 1, soluble |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
TPX2 | TPX2, microtubule-associated |
TRIP13 | thyroid hormone receptor interactor 13 |
UBE2C | ubiquitin-conjugating enzyme E2C |