BRD-K30867024_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K30867024_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ANXA1 annexin A1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
CAST calpastatin
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DIO1 deiodinase, iodothyronine, type I
EPRS glutamyl-prolyl-tRNA synthetase
F11R F11 receptor
GARS glycyl-tRNA synthetase
GREM1 gremlin 1, DAN family BMP antagonist
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
INHBA inhibin, beta A
INHBE inhibin, beta E
MAN1A1 mannosidase, alpha, class 1A, member 1
MARS methionyl-tRNA synthetase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYC v-myc avian myelocytomatosis viral oncogene homolog
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
SCGB2A2 secretoglobin, family 2A, member 2
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
TES testin LIM domain protein
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
WARS tryptophanyl-tRNA synthetase
XPOT exportin, tRNA
YARS tyrosyl-tRNA synthetase

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AZU1 azurocidin 1
CHL1 cell adhesion molecule L1-like
CTSG cathepsin G
CYBB cytochrome b-245, beta polypeptide
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
GPATCH8 G patch domain containing 8
HSPA8 heat shock 70kDa protein 8
MFSD10 major facilitator superfamily domain containing 10
SLPI secretory leukocyte peptidase inhibitor
Funding