Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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48 genes differentially expressed following the BRD-K31238592_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABHD4 | abhydrolase domain containing 4 |
BAG3 | BCL2-associated athanogene 3 |
C1ORF115 | chromosome 1 open reading frame 115 |
CACYBP | calcyclin binding protein |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CHI3L2 | chitinase 3-like 2 |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
CLU | clusterin |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
FAS | Fas cell surface death receptor |
GCLM | glutamate-cysteine ligase, modifier subunit |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HMOX1 | heme oxygenase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
HSPE1 | heat shock 10kDa protein 1 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
NELL2 | NEL-like 2 (chicken) |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SQSTM1 | sequestosome 1 |
ZW10 | zw10 kinetochore protein |
Symbol | Name |
---|---|
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CCND1 | cyclin D1 |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DUOX2 | dual oxidase 2 |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IGFBP3 | insulin-like growth factor binding protein 3 |
IGFBP7 | insulin-like growth factor binding protein 7 |
KRT23 | keratin 23, type I |
LUM | lumican |
NKG7 | natural killer cell granule protein 7 |
PLN | phospholamban |
PRSS23 | protease, serine, 23 |
RGS13 | regulator of G-protein signaling 13 |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SLC38A10 | solute carrier family 38, member 10 |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
TYRP1 | tyrosinase-related protein 1 |