Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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96 genes differentially expressed following the BRD-K31412180_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACKR3 | atypical chemokine receptor 3 |
ADA | adenosine deaminase |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
ARL4C | ADP-ribosylation factor-like 4C |
ARMCX2 | armadillo repeat containing, X-linked 2 |
ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CCDC86 | coiled-coil domain containing 86 |
CD200 | CD200 molecule |
CD9 | CD9 molecule |
CD93 | CD93 molecule |
CDH13 | cadherin 13 |
CHEK1 | checkpoint kinase 1 |
COL8A2 | collagen, type VIII, alpha 2 |
CORO1A | coronin, actin binding protein, 1A |
CPE | carboxypeptidase E |
CREB1 | cAMP responsive element binding protein 1 |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
DOCK4 | dedicator of cytokinesis 4 |
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
FLT1 | fms-related tyrosine kinase 1 |
GJA1 | gap junction protein, alpha 1, 43kDa |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
IL1R1 | interleukin 1 receptor, type I |
KIAA0196 | KIAA0196 |
KRT23 | keratin 23, type I |
LMO3 | LIM domain only 3 (rhombotin-like 2) |
LPAR6 | lysophosphatidic acid receptor 6 |
MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
MMP2 | matrix metallopeptidase 2 |
NPTX2 | neuronal pentraxin II |
PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
PAPD7 | PAP associated domain containing 7 |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PRKCI | protein kinase C, iota |
PRKX | protein kinase, X-linked |
PXDN | peroxidasin |
RGCC | regulator of cell cycle |
RGS5 | regulator of G-protein signaling 5 |
RND3 | Rho family GTPase 3 |
RSU1 | Ras suppressor protein 1 |
RTN2 | reticulon 2 |
SDC1 | syndecan 1 |
SNX7 | sorting nexin 7 |
SOD2 | superoxide dismutase 2, mitochondrial |
SOX2 | SRY (sex determining region Y)-box 2 |
SPARCL1 | SPARC-like 1 (hevin) |
SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
SULF1 | sulfatase 1 |
TCF4 | transcription factor 4 |
TGFB3 | transforming growth factor, beta 3 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TPSAB1 | tryptase alpha/beta 1 |
TTC39A | tetratricopeptide repeat domain 39A |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
XIST | X inactive specific transcript (non-protein coding) |
Symbol | Name |
---|---|
AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
APOA1 | apolipoprotein A-I |
APOA2 | apolipoprotein A-II |
AQP3 | aquaporin 3 (Gill blood group) |
CASP7 | caspase 7, apoptosis-related cysteine peptidase |
CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
COL9A3 | collagen, type IX, alpha 3 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DSP | desmoplakin |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
FAM46A | family with sequence similarity 46, member A |
HN1 | hematological and neurological expressed 1 |
JMJD6 | jumonji domain containing 6 |
KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 |
KDM5D | lysine (K)-specific demethylase 5D |
KIF20A | kinesin family member 20A |
LTF | lactotransferrin |
MAMLD1 | mastermind-like domain containing 1 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MSX1 | msh homeobox 1 |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SFRP1 | secreted frizzled-related protein 1 |
SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
STAT1 | signal transducer and activator of transcription 1, 91kDa |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TGFBR3 | transforming growth factor, beta receptor III |
TMBIM6 | transmembrane BAX inhibitor motif containing 6 |