Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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104 genes differentially expressed following the BRD-K31688005_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ARHGAP29 | Rho GTPase activating protein 29 |
ASCL1 | achaete-scute family bHLH transcription factor 1 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
CA2 | carbonic anhydrase II |
CAMP | cathelicidin antimicrobial peptide |
CCL4 | chemokine (C-C motif) ligand 4 |
CCND2 | cyclin D2 |
CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 |
CLC | Charcot-Leyden crystal galectin |
CLEC2B | C-type lectin domain family 2, member B |
COL11A1 | collagen, type XI, alpha 1 |
CP | ceruloplasmin (ferroxidase) |
CPE | carboxypeptidase E |
CXORF57 | chromosome X open reading frame 57 |
DEFA4 | defensin, alpha 4, corticostatin |
ERBB4 | erb-b2 receptor tyrosine kinase 4 |
GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
HHEX | hematopoietically expressed homeobox |
IGFBP5 | insulin-like growth factor binding protein 5 |
JUP | junction plakoglobin |
KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
KCTD14 | potassium channel tetramerization domain containing 14 |
KRT19 | keratin 19, type I |
KRT23 | keratin 23, type I |
LPAR6 | lysophosphatidic acid receptor 6 |
MEF2C | myocyte enhancer factor 2C |
MFAP5 | microfibrillar associated protein 5 |
MMP9 | matrix metallopeptidase 9 |
NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
NPTX2 | neuronal pentraxin II |
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
PEG3 | paternally expressed 3 |
PERP | PERP, TP53 apoptosis effector |
PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
PROM1 | prominin 1 |
REEP5 | receptor accessory protein 5 |
RGS5 | regulator of G-protein signaling 5 |
RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
RNF44 | ring finger protein 44 |
SOX11 | SRY (sex determining region Y)-box 11 |
SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
SULF1 | sulfatase 1 |
TERT | telomerase reverse transcriptase |
TGFA | transforming growth factor, alpha |
TSPAN12 | tetraspanin 12 |
VAV3 | vav 3 guanine nucleotide exchange factor |
VNN1 | vanin 1 |
VSNL1 | visinin-like 1 |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
Symbol | Name |
---|---|
ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
AK1 | adenylate kinase 1 |
AP1S2 | adaptor-related protein complex 1, sigma 2 subunit |
ATMIN | ATM interactor |
BST2 | bone marrow stromal cell antigen 2 |
CAST | calpastatin |
CDC20 | cell division cycle 20 |
CTSB | cathepsin B |
DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
ECI2 | enoyl-CoA delta isomerase 2 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FBLN1 | fibulin 1 |
FOXO1 | forkhead box O1 |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GNAS | GNAS complex locus |
HK1 | hexokinase 1 |
IGFBP4 | insulin-like growth factor binding protein 4 |
IL7R | interleukin 7 receptor |
KIF14 | kinesin family member 14 |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LPAR1 | lysophosphatidic acid receptor 1 |
MSRB2 | methionine sulfoxide reductase B2 |
MSX1 | msh homeobox 1 |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
NES | nestin |
OLFML3 | olfactomedin-like 3 |
OPN3 | opsin 3 |
PGD | phosphogluconate dehydrogenase |
PLAC8 | placenta-specific 8 |
PLAT | plasminogen activator, tissue |
PRDX6 | peroxiredoxin 6 |
PRKCA | protein kinase C, alpha |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
RCAN1 | regulator of calcineurin 1 |
RHOA | ras homolog family member A |
SLC30A9 | solute carrier family 30 (zinc transporter), member 9 |
SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
SRPX | sushi-repeat containing protein, X-linked |
TGM2 | transglutaminase 2 |
TMEM251 | transmembrane protein 251 |
TSPAN3 | tetraspanin 3 |
UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
UGCG | UDP-glucose ceramide glucosyltransferase |
USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
WBSCR22 | Williams Beuren syndrome chromosome region 22 |
XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
ZNF185 | zinc finger protein 185 (LIM domain) |