BRD-K31699485_-666_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

115 genes differentially expressed following the BRD-K31699485_-666_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACSL1 acyl-CoA synthetase long-chain family member 1
ADIPOQ adiponectin, C1Q and collagen domain containing
CADM1 cell adhesion molecule 1
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCR7 chemokine (C-C motif) receptor 7
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CP ceruloplasmin (ferroxidase)
DLK1 delta-like 1 homolog (Drosophila)
DLX5 distal-less homeobox 5
EPCAM epithelial cell adhesion molecule
EREG epiregulin
GHR growth hormone receptor
GPX3 glutathione peroxidase 3
HBB hemoglobin, beta
HOXB2 homeobox B2
HP haptoglobin
IGSF3 immunoglobulin superfamily, member 3
IL1R1 interleukin 1 receptor, type I
KIAA0125 KIAA0125
LOC100505650 uncharacterized LOC100505650
MAGEA6 melanoma antigen family A6
MECOM MDS1 and EVI1 complex locus
PAX8 paired box 8
PLIN1 perilipin 1
PRAME preferentially expressed antigen in melanoma
PRSS21 protease, serine, 21 (testisin)
RGS16 regulator of G-protein signaling 16
SFN stratifin
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLPI secretory leukocyte peptidase inhibitor
SYNGR3 synaptogyrin 3
TKTL1 transketolase-like 1
TNC tenascin C
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
TXNIP thioredoxin interacting protein
UPK1B uroplakin 1B
WDR91 WD repeat domain 91
WFDC2 WAP four-disulfide core domain 2
ZCCHC14 zinc finger, CCHC domain containing 14

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AMZ2 archaelysin family metallopeptidase 2
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
BID BH3 interacting domain death agonist
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CAV1 caveolin 1, caveolae protein, 22kDa
CELF2 CUGBP, Elav-like family member 2
CHPT1 choline phosphotransferase 1
CLTB clathrin, light chain B
COPS7A COP9 signalosome subunit 7A
CRABP2 cellular retinoic acid binding protein 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CXCL13 chemokine (C-X-C motif) ligand 13
DTNA dystrobrevin, alpha
EIF5 eukaryotic translation initiation factor 5
FABP7 fatty acid binding protein 7, brain
FBP1 fructose-1,6-bisphosphatase 1
FBXO21 F-box protein 21
FSTL1 follistatin-like 1
GALC galactosylceramidase
GATA6 GATA binding protein 6
GPM6B glycoprotein M6B
GTF3A general transcription factor IIIA
GTPBP8 GTP-binding protein 8 (putative)
GUSBP11 glucuronidase, beta pseudogene 11
H2AFY H2A histone family, member Y
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HN1 hematological and neurological expressed 1
HSPH1 heat shock 105kDa/110kDa protein 1
JMJD6 jumonji domain containing 6
LAMP2 lysosomal-associated membrane protein 2
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LY96 lymphocyte antigen 96
LYZ lysozyme
MARCKS myristoylated alanine-rich protein kinase C substrate
MME membrane metallo-endopeptidase
MRPL57 mitochondrial ribosomal protein L57
MRPS16 mitochondrial ribosomal protein S16
MZB1 marginal zone B and B1 cell-specific protein
NPEPL1 aminopeptidase-like 1
PDLIM5 PDZ and LIM domain 5
PECAM1 platelet/endothelial cell adhesion molecule 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLA2G16 phospholipase A2, group XVI
PLBD1 phospholipase B domain containing 1
PLN phospholamban
PMP22 peripheral myelin protein 22
POLR1D polymerase (RNA) I polypeptide D, 16kDa
PON2 paraoxonase 2
PRUNE2 prune homolog 2 (Drosophila)
PTEN phosphatase and tensin homolog
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYCARD PYD and CARD domain containing
RFTN1 raftlin, lipid raft linker 1
RNASE6 ribonuclease, RNase A family, k6
RND3 Rho family GTPase 3
RNF167 ring finger protein 167
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPATS2L spermatogenesis associated, serine-rich 2-like
SPINK1 serine peptidase inhibitor, Kazal type 1
SSFA2 sperm specific antigen 2
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TPD52L2 tumor protein D52-like 2
TPM4 tropomyosin 4
TUBB2A tubulin, beta 2A class IIa
TYROBP TYRO protein tyrosine kinase binding protein
YBX3 Y box binding protein 3
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZFP36L2 ZFP36 ring finger protein-like 2
Funding