BRD-K31887147_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K31887147_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP1 aquaporin 1 (Colton blood group)
AUTS2 autism susceptibility candidate 2
BLNK B-cell linker
C6ORF62 chromosome 6 open reading frame 62
CA2 carbonic anhydrase II
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL1A2 collagen, type I, alpha 2
DUSP2 dual specificity phosphatase 2
FHL1 four and a half LIM domains 1
GPNMB glycoprotein (transmembrane) nmb
HMBOX1 homeobox containing 1
NEBL nebulette
SPARCL1 SPARC-like 1 (hevin)
SPRED2 sprouty-related, EVH1 domain containing 2
THBS2 thrombospondin 2

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
CD151 CD151 molecule (Raph blood group)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
FADS1 fatty acid desaturase 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FLNB filamin B, beta
FSTL1 follistatin-like 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
KRT7 keratin 7, type II
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
NUDCD3 NudC domain containing 3
PDGFC platelet derived growth factor C
PMEPA1 prostate transmembrane protein, androgen induced 1
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
RABAC1 Rab acceptor 1 (prenylated)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SRGN serglycin
STK17A serine/threonine kinase 17a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNPO1 transportin 1
TSPAN4 tetraspanin 4