BRD-K32238524_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K32238524_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD24 CD24 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL7A1 collagen, type VII, alpha 1
CXCL5 chemokine (C-X-C motif) ligand 5
FKBP11 FK506 binding protein 11, 19 kDa
FOLR1 folate receptor 1 (adult)
GCLC glutamate-cysteine ligase, catalytic subunit
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSTA4 glutathione S-transferase alpha 4
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV1-40 immunoglobulin lambda variable 1-40
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
LGALS8 lectin, galactoside-binding, soluble, 8
LTF lactotransferrin
QPCT glutaminyl-peptide cyclotransferase
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TNFAIP2 tumor necrosis factor, alpha-induced protein 2

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ALB albumin
ARHGAP29 Rho GTPase activating protein 29
ASPN asporin
CCND1 cyclin D1
CPE carboxypeptidase E
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGEA3 melanoma antigen family A3
MFAP5 microfibrillar associated protein 5
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MYH10 myosin, heavy chain 10, non-muscle
NGRN neugrin, neurite outgrowth associated
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLN phospholamban
PVALB parvalbumin
SFRP1 secreted frizzled-related protein 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TACSTD2 tumor-associated calcium signal transducer 2
TES testin LIM domain protein
TFPI2 tissue factor pathway inhibitor 2
TSPYL5 TSPY-like 5
TUSC3 tumor suppressor candidate 3