Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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105 genes differentially expressed following the BRD-K32238524_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
AMPD3 | adenosine monophosphate deaminase 3 |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
BCHE | butyrylcholinesterase |
C6ORF48 | chromosome 6 open reading frame 48 |
CCL5 | chemokine (C-C motif) ligand 5 |
CCND2 | cyclin D2 |
CDK6 | cyclin-dependent kinase 6 |
CDKN2A | cyclin-dependent kinase inhibitor 2A |
CFB | complement factor B |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CHODL | chondrolectin |
CLGN | calmegin |
COL4A5 | collagen, type IV, alpha 5 |
DDIT4 | DNA-damage-inducible transcript 4 |
ETV1 | ets variant 1 |
FAM129A | family with sequence similarity 129, member A |
FAM63A | family with sequence similarity 63, member A |
FBN2 | fibrillin 2 |
FBXL12 | F-box and leucine-rich repeat protein 12 |
GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) |
HBD | hemoglobin, delta |
IL32 | interleukin 32 |
KLRK1 | killer cell lectin-like receptor subfamily K, member 1 |
LCN2 | lipocalin 2 |
LEF1 | lymphoid enhancer-binding factor 1 |
LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
LTB | lymphotoxin beta (TNF superfamily, member 3) |
LYPD1 | LY6/PLAUR domain containing 1 |
MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
MMP9 | matrix metallopeptidase 9 |
MTSS1 | metastasis suppressor 1 |
PRKCQ | protein kinase C, theta |
PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
RAB4A | RAB4A, member RAS oncogene family |
RGS2 | regulator of G-protein signaling 2 |
SCG5 | secretogranin V |
SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
SOD2 | superoxide dismutase 2, mitochondrial |
SPON2 | spondin 2, extracellular matrix protein |
TRD | T cell receptor delta locus |
TSC22D1 | TSC22 domain family, member 1 |
UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
VEGFA | vascular endothelial growth factor A |
Symbol | Name |
---|---|
ACTA2 | actin, alpha 2, smooth muscle, aorta |
ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide |
ADIRF | adipogenesis regulatory factor |
AGR2 | anterior gradient 2 |
AHR | aryl hydrocarbon receptor |
AKR1C3 | aldo-keto reductase family 1, member C3 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
CD200 | CD200 molecule |
CD24 | CD24 molecule |
CD59 | CD59 molecule, complement regulatory protein |
CDCA4 | cell division cycle associated 4 |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
COLEC11 | collectin sub-family member 11 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
EMP1 | epithelial membrane protein 1 |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
EPS8 | epidermal growth factor receptor pathway substrate 8 |
FBP1 | fructose-1,6-bisphosphatase 1 |
FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
FZD7 | frizzled class receptor 7 |
GPNMB | glycoprotein (transmembrane) nmb |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
GSTA1 | glutathione S-transferase alpha 1 |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
IFI44L | interferon-induced protein 44-like |
IGFBP6 | insulin-like growth factor binding protein 6 |
IGL | immunoglobulin lambda locus |
ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
KRT19 | keratin 19, type I |
KYNU | kynureninase |
LGALS3 | lectin, galactoside-binding, soluble, 3 |
MAP7 | microtubule-associated protein 7 |
MGLL | monoglyceride lipase |
MYH11 | myosin, heavy chain 11, smooth muscle |
MYO1B | myosin IB |
NPR3 | natriuretic peptide receptor 3 |
PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
PLAC8 | placenta-specific 8 |
PODXL | podocalyxin-like |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PSCA | prostate stem cell antigen |
RHOBTB3 | Rho-related BTB domain containing 3 |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
SATB1 | SATB homeobox 1 |
SDC1 | syndecan 1 |
SDC4 | syndecan 4 |
SFN | stratifin |
SWAP70 | SWAP switching B-cell complex 70kDa subunit |
TOX3 | TOX high mobility group box family member 3 |
TSPAN8 | tetraspanin 8 |
UBE2G2 | ubiquitin-conjugating enzyme E2G 2 |
VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) |
ZNF652 | zinc finger protein 652 |