| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
135 genes differentially expressed following the BRD-K32292990_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AREG | amphiregulin |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATG3 | autophagy related 3 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD9 | CD9 molecule |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| COL10A1 | collagen, type X, alpha 1 |
| CPM | carboxypeptidase M |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) |
| EVI2A | ecotropic viral integration site 2A |
| F11R | F11 receptor |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| ICAM1 | intercellular adhesion molecule 1 |
| IER2 | immediate early response 2 |
| IER3 | immediate early response 3 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL4R | interleukin 4 receptor |
| INHBA | inhibin, beta A |
| INPP1 | inositol polyphosphate-1-phosphatase |
| JUNB | jun B proto-oncogene |
| KDM6B | lysine (K)-specific demethylase 6B |
| KLF4 | Kruppel-like factor 4 (gut) |
| KRT14 | keratin 14, type I |
| LIF | leukemia inhibitory factor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MCL1 | myeloid cell leukemia 1 |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAT | plasminogen activator, tissue |
| PLAU | plasminogen activator, urokinase |
| PTX3 | pentraxin 3, long |
| RSF1 | remodeling and spacing factor 1 |
| S100A6 | S100 calcium binding protein A6 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| STAR | steroidogenic acute regulatory protein |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| THBS1 | thrombospondin 1 |
| TJP2 | tight junction protein 2 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRIB1 | tribbles pseudokinase 1 |
| TXNIP | thioredoxin interacting protein |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| B3GNT1 | |
| BEX1 | brain expressed, X-linked 1 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BRCA1 | breast cancer 1, early onset |
| C1S | complement component 1, s subcomponent |
| CD99 | CD99 molecule |
| CDC25B | cell division cycle 25B |
| COL3A1 | collagen, type III, alpha 1 |
| DAPK1 | death-associated protein kinase 1 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FABP7 | fatty acid binding protein 7, brain |
| FAM134B | family with sequence similarity 134, member B |
| FGB | fibrinogen beta chain |
| FHL1 | four and a half LIM domains 1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| GAS2 | growth arrest-specific 2 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GYG2 | glycogenin 2 |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPB8 | heat shock 22kDa protein 8 |
| IFI44 | interferon-induced protein 44 |
| ITM2A | integral membrane protein 2A |
| LRRN3 | leucine rich repeat neuronal 3 |
| MCAM | melanoma cell adhesion molecule |
| METTL3 | methyltransferase like 3 |
| MID1 | midline 1 |
| MSH6 | mutS homolog 6 |
| MTMR4 | myotubularin related protein 4 |
| NDRG3 | NDRG family member 3 |
| NUP62 | nucleoporin 62kDa |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PDZK1 | PDZ domain containing 1 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLK1 | polo-like kinase 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRKCA | protein kinase C, alpha |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RBP1 | retinol binding protein 1, cellular |
| REEP1 | receptor accessory protein 1 |
| REG1A | regenerating islet-derived 1 alpha |
| RGS1 | regulator of G-protein signaling 1 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RPS11 | ribosomal protein S11 |
| SALL2 | spalt-like transcription factor 2 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SOX11 | SRY (sex determining region Y)-box 11 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TMEM97 | transmembrane protein 97 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TUBB | tubulin, beta class I |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
