BRD-K32405725_E933505_MCF7_24.0_h_88.8_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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34 genes differentially expressed following the BRD-K32405725_E933505_MCF7_24.0_h_88.8_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADIRF adipogenesis regulatory factor
CTSH cathepsin H
DFNA5 deafness, autosomal dominant 5
DSP desmoplakin
EPAS1 endothelial PAS domain protein 1
GSN gelsolin
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
LAMP3 lysosomal-associated membrane protein 3
NTS neurotensin
PHGDH phosphoglycerate dehydrogenase
PYGL phosphorylase, glycogen, liver
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A6 S100 calcium binding protein A6
SAT1 spermidine/spermine N1-acetyltransferase 1
SFTPB surfactant protein B
SLC38A1 solute carrier family 38, member 1
TNS3 tensin 3
TPSAB1 tryptase alpha/beta 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF5 activating transcription factor 5
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CXCL12 chemokine (C-X-C motif) ligand 12
GLUL glutamate-ammonia ligase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MCM7 minichromosome maintenance complex component 7
MSH6 mutS homolog 6
NUSAP1 nucleolar and spindle associated protein 1
PMPCA peptidase (mitochondrial processing) alpha
RFC2 replication factor C (activator 1) 2, 40kDa
RRM2 ribonucleotide reductase M2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TMEM45A transmembrane protein 45A
ZWINT ZW10 interacting kinetochore protein