BRD-K32485462_-666_HT29_6.0_h_10.0_um Gene Set
Genes
33 genes differentially expressed following the BRD-K32485462_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
Symbol |
Name |
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
C3
|
complement component 3
|
CDK14
|
cyclin-dependent kinase 14
|
CXADR
|
coxsackie virus and adenovirus receptor
|
CYP51A1
|
cytochrome P450, family 51, subfamily A, polypeptide 1
|
DHCR24
|
24-dehydrocholesterol reductase
|
DHCR7
|
7-dehydrocholesterol reductase
|
EIF5A
|
eukaryotic translation initiation factor 5A
|
FADS1
|
fatty acid desaturase 1
|
FADS2
|
fatty acid desaturase 2
|
FAM117A
|
family with sequence similarity 117, member A
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
IDI1
|
isopentenyl-diphosphate delta isomerase 1
|
INSIG1
|
insulin induced gene 1
|
JUND
|
jun D proto-oncogene
|
LSS
|
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
|
MSMO1
|
methylsterol monooxygenase 1
|
RHOB
|
ras homolog family member B
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
SC5D
|
sterol-C5-desaturase
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
SQLE
|
squalene epoxidase
|
TMEM97
|
transmembrane protein 97
|
UBE2J1
|
ubiquitin-conjugating enzyme E2, J1
|
decreased expression
Symbol |
Name |
HBEGF
|
heparin-binding EGF-like growth factor
|
IL1R2
|
interleukin 1 receptor, type II
|
LGALS3BP
|
lectin, galactoside-binding, soluble, 3 binding protein
|
MMP9
|
matrix metallopeptidase 9
|
MYBPC1
|
myosin binding protein C, slow type
|
UCK2
|
uridine-cytidine kinase 2
|