BRD-K32827536_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K32827536_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA6 annexin A6
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BCL2A1 BCL2-related protein A1
CD59 CD59 molecule, complement regulatory protein
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
GSTA4 glutathione S-transferase alpha 4
IGFBP3 insulin-like growth factor binding protein 3
IL2RB interleukin 2 receptor, beta
MCOLN1 mucolipin 1
RHOB ras homolog family member B
RHOBTB3 Rho-related BTB domain containing 3
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SORD sorbitol dehydrogenase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMEM2 transmembrane protein 2

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
APOB apolipoprotein B
ARHGAP29 Rho GTPase activating protein 29
C7 complement component 7
CD200 CD200 molecule
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM69A family with sequence similarity 69, member A
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FILIP1L filamin A interacting protein 1-like
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HDAC9 histone deacetylase 9
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
JAG1 jagged 1
JCHAIN joining chain of multimeric IgA and IgM
KRT8 keratin 8, type II
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
NPTX1 neuronal pentraxin I
NR2F1 nuclear receptor subfamily 2, group F, member 1
NT5E 5'-nucleotidase, ecto (CD73)
OLFM4 olfactomedin 4
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PTGIS prostaglandin I2 (prostacyclin) synthase
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SCGB2A1 secretoglobin, family 2A, member 1
SPON1 spondin 1, extracellular matrix protein
STC1 stanniocalcin 1
STS steroid sulfatase (microsomal), isozyme S
TFPI2 tissue factor pathway inhibitor 2
TSPAN12 tetraspanin 12