Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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107 genes differentially expressed following the BRD-K33106058_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
APOLD1 | apolipoprotein L domain containing 1 |
AQP1 | aquaporin 1 (Colton blood group) |
AUTS2 | autism susceptibility candidate 2 |
BHLHE41 | basic helix-loop-helix family, member e41 |
BTG2 | BTG family, member 2 |
CBS | cystathionine-beta-synthase |
CD24 | CD24 molecule |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CLU | clusterin |
CNPY3 | canopy FGF signaling regulator 3 |
COL11A1 | collagen, type XI, alpha 1 |
DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
DHDDS | dehydrodolichyl diphosphate synthase |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DLK1 | delta-like 1 homolog (Drosophila) |
EGFL6 | EGF-like-domain, multiple 6 |
EGR1 | early growth response 1 |
EGR2 | early growth response 2 |
EGR3 | early growth response 3 |
EIF5A | eukaryotic translation initiation factor 5A |
EREG | epiregulin |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FHL1 | four and a half LIM domains 1 |
FOLR1 | folate receptor 1 (adult) |
GCH1 | GTP cyclohydrolase 1 |
GREM1 | gremlin 1, DAN family BMP antagonist |
HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
LAMP3 | lysosomal-associated membrane protein 3 |
LEF1 | lymphoid enhancer-binding factor 1 |
LPL | lipoprotein lipase |
LTBP1 | latent transforming growth factor beta binding protein 1 |
MATN2 | matrilin 2 |
MGLL | monoglyceride lipase |
MOXD1 | monooxygenase, DBH-like 1 |
NID2 | nidogen 2 (osteonidogen) |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
OPN3 | opsin 3 |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PER1 | period circadian clock 1 |
PRSS21 | protease, serine, 21 (testisin) |
RCAN1 | regulator of calcineurin 1 |
RRBP1 | ribosome binding protein 1 |
SCG5 | secretogranin V |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SESN1 | sestrin 1 |
SFTPA2 | surfactant protein A2 |
SFTPB | surfactant protein B |
SFTPC | surfactant protein C |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
STC2 | stanniocalcin 2 |
TDO2 | tryptophan 2,3-dioxygenase |
TFF3 | trefoil factor 3 (intestinal) |
TIMP4 | TIMP metallopeptidase inhibitor 4 |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
TPD52L1 | tumor protein D52-like 1 |
TRIM22 | tripartite motif containing 22 |
TWIST1 | twist family bHLH transcription factor 1 |
ZNF331 | zinc finger protein 331 |
Symbol | Name |
---|---|
CAST | calpastatin |
CCNB1 | cyclin B1 |
CCP110 | centriolar coiled coil protein 110kDa |
CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) |
COPS7A | COP9 signalosome subunit 7A |
CPNE1 | copine I |
CRABP2 | cellular retinoic acid binding protein 2 |
CREG1 | cellular repressor of E1A-stimulated genes 1 |
DPYSL2 | dihydropyrimidinase-like 2 |
EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
EFNA1 | ephrin-A1 |
FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) |
GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
ITGB1BP1 | integrin beta 1 binding protein 1 |
KIF20A | kinesin family member 20A |
KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
LGALS1 | lectin, galactoside-binding, soluble, 1 |
LOC100505650 | uncharacterized LOC100505650 |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
METTL9 | methyltransferase like 9 |
MRPS2 | mitochondrial ribosomal protein S2 |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 |
PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
PLK1 | polo-like kinase 1 |
PLK2 | polo-like kinase 2 |
PROM1 | prominin 1 |
PWP1 | PWP1 homolog (S. cerevisiae) |
QPCT | glutaminyl-peptide cyclotransferase |
RAI14 | retinoic acid induced 14 |
RFC5 | replication factor C (activator 1) 5, 36.5kDa |
RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
RTN2 | reticulon 2 |
SCAND1 | SCAN domain containing 1 |
SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TM4SF1 | transmembrane 4 L six family member 1 |
TMEM176B | transmembrane protein 176B |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
UBE2S | ubiquitin-conjugating enzyme E2S |
UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
VCAN | versican |
ZFP36L2 | ZFP36 ring finger protein-like 2 |