BRD-K33106058_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K33106058_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOLD1 apolipoprotein L domain containing 1
AQP1 aquaporin 1 (Colton blood group)
AUTS2 autism susceptibility candidate 2
BHLHE41 basic helix-loop-helix family, member e41
BTG2 BTG family, member 2
CBS cystathionine-beta-synthase
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLU clusterin
CNPY3 canopy FGF signaling regulator 3
COL11A1 collagen, type XI, alpha 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHDDS dehydrodolichyl diphosphate synthase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
EGFL6 EGF-like-domain, multiple 6
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
EREG epiregulin
F3 coagulation factor III (thromboplastin, tissue factor)
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
GCH1 GTP cyclohydrolase 1
GREM1 gremlin 1, DAN family BMP antagonist
HACD2 3-hydroxyacyl-CoA dehydratase 2
LAMP3 lysosomal-associated membrane protein 3
LEF1 lymphoid enhancer-binding factor 1
LPL lipoprotein lipase
LTBP1 latent transforming growth factor beta binding protein 1
MATN2 matrilin 2
MGLL monoglyceride lipase
MOXD1 monooxygenase, DBH-like 1
NID2 nidogen 2 (osteonidogen)
NQO1 NAD(P)H dehydrogenase, quinone 1
OPN3 opsin 3
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PER1 period circadian clock 1
PRSS21 protease, serine, 21 (testisin)
RCAN1 regulator of calcineurin 1
RRBP1 ribosome binding protein 1
SCG5 secretogranin V
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SESN1 sestrin 1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STC2 stanniocalcin 2
TDO2 tryptophan 2,3-dioxygenase
TFF3 trefoil factor 3 (intestinal)
TIMP4 TIMP metallopeptidase inhibitor 4
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TPD52L1 tumor protein D52-like 1
TRIM22 tripartite motif containing 22
TWIST1 twist family bHLH transcription factor 1
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
CAST calpastatin
CCNB1 cyclin B1
CCP110 centriolar coiled coil protein 110kDa
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CIAPIN1 cytokine induced apoptosis inhibitor 1
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
COPS7A COP9 signalosome subunit 7A
CPNE1 copine I
CRABP2 cellular retinoic acid binding protein 2
CREG1 cellular repressor of E1A-stimulated genes 1
DPYSL2 dihydropyrimidinase-like 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNA1 ephrin-A1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
ITGB1BP1 integrin beta 1 binding protein 1
KIF20A kinesin family member 20A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LGALS1 lectin, galactoside-binding, soluble, 1
LOC100505650 uncharacterized LOC100505650
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
METTL9 methyltransferase like 9
MRPS2 mitochondrial ribosomal protein S2
NR2F2 nuclear receptor subfamily 2, group F, member 2
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PROM1 prominin 1
PWP1 PWP1 homolog (S. cerevisiae)
QPCT glutaminyl-peptide cyclotransferase
RAI14 retinoic acid induced 14
RFC5 replication factor C (activator 1) 5, 36.5kDa
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RTN2 reticulon 2
SCAND1 SCAN domain containing 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM4SF1 transmembrane 4 L six family member 1
TMEM176B transmembrane protein 176B
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2S ubiquitin-conjugating enzyme E2S
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
VCAN versican
ZFP36L2 ZFP36 ring finger protein-like 2