| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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188 genes differentially expressed following the BRD-K33272502_DG-041_A549_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ARMCX3 | armadillo repeat containing, X-linked 3 |
| ASS1 | argininosuccinate synthase 1 |
| ATF3 | activating transcription factor 3 |
| BAG3 | BCL2-associated athanogene 3 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CPE | carboxypeptidase E |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CTTN | cortactin |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| EMP1 | epithelial membrane protein 1 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| G0S2 | G0/G1 switch 2 |
| GAB2 | GRB2-associated binding protein 2 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GUSBP11 | glucuronidase, beta pseudogene 11 |
| H1F0 | H1 histone family, member 0 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HLA-B | major histocompatibility complex, class I, B |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HLA-E | major histocompatibility complex, class I, E |
| HSPA1A | heat shock 70kDa protein 1A |
| IER3 | immediate early response 3 |
| IER5 | immediate early response 5 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFRD1 | interferon-related developmental regulator 1 |
| IGL | immunoglobulin lambda locus |
| IL1A | interleukin 1, alpha |
| IL6 | interleukin 6 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| JUN | jun proto-oncogene |
| KLF6 | Kruppel-like factor 6 |
| KRT14 | keratin 14, type I |
| LAMB3 | laminin, beta 3 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LDLR | low density lipoprotein receptor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCL1 | myeloid cell leukemia 1 |
| MGLL | monoglyceride lipase |
| MMP1 | matrix metallopeptidase 1 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NUCB2 | nucleobindin 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSR2 | odd-skipped related transciption factor 2 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTX3 | pentraxin 3, long |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGCC | regulator of cell cycle |
| RGS5 | regulator of G-protein signaling 5 |
| RND3 | Rho family GTPase 3 |
| SARS | seryl-tRNA synthetase |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPON2 | spondin 2, extracellular matrix protein |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| STC2 | stanniocalcin 2 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM2 | tripartite motif containing 2 |
| UFM1 | ubiquitin-fold modifier 1 |
| VEGFA | vascular endothelial growth factor A |
| VWF | von Willebrand factor |
| WDR45 | WD repeat domain 45 |
| XBP1 | X-box binding protein 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ADD3 | adducin 3 (gamma) |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ASF1B | anti-silencing function 1B histone chaperone |
| B3GNT1 | |
| BIRC5 | baculoviral IAP repeat containing 5 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CALD1 | caldesmon 1 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CASP6 | caspase 6, apoptosis-related cysteine peptidase |
| CCNA2 | cyclin A2 |
| CDK1 | cyclin-dependent kinase 1 |
| CLU | clusterin |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CRIP2 | cysteine-rich protein 2 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EML4 | echinoderm microtubule associated protein like 4 |
| F2R | coagulation factor II (thrombin) receptor |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FGA | fibrinogen alpha chain |
| FGB | fibrinogen beta chain |
| FGFR3 | fibroblast growth factor receptor 3 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GPX2 | glutathione peroxidase 2 |
| GPX3 | glutathione peroxidase 3 |
| HADH | hydroxyacyl-CoA dehydrogenase |
| HMGB3 | high mobility group box 3 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HOXC6 | homeobox C6 |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIF14 | kinesin family member 14 |
| LBH | limb bud and heart development |
| LBR | lamin B receptor |
| LIPA | lipase A, lysosomal acid, cholesterol esterase |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAP2K6 | mitogen-activated protein kinase kinase 6 |
| MARCKSL1 | MARCKS-like 1 |
| MPHOSPH9 | M-phase phosphoprotein 9 |
| MYCBP | MYC binding protein |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NPY | neuropeptide Y |
| NTS | neurotensin |
| NUP210 | nucleoporin 210kDa |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PCNA | proliferating cell nuclear antigen |
| PHACTR2 | phosphatase and actin regulator 2 |
| PLK1 | polo-like kinase 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRKCB | protein kinase C, beta |
| PROS1 | protein S (alpha) |
| PRSS23 | protease, serine, 23 |
| PSPH | phosphoserine phosphatase |
| PTER | phosphotriesterase related |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| RAD51C | RAD51 paralog C |
| RPA3 | replication protein A3, 14kDa |
| RPS11 | ribosomal protein S11 |
| SEPHS1 | selenophosphate synthetase 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SKP1 | S-phase kinase-associated protein 1 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SPP1 | secreted phosphoprotein 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STRA13 | stimulated by retinoic acid 13 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TCTN1 | tectonic family member 1 |
| TESC | tescalcin |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TMEM14A | transmembrane protein 14A |
| TMEM2 | transmembrane protein 2 |
| TMEM47 | transmembrane protein 47 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN6 | tetraspanin 6 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UGDH | UDP-glucose 6-dehydrogenase |
| UPK1B | uroplakin 1B |
| VCAN | versican |
