| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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253 genes differentially expressed following the BRD-K33272502_DG-041_HT29_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AARS | alanyl-tRNA synthetase |
| ACVR1 | activin A receptor, type I |
| ADM | adrenomedullin |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ANXA1 | annexin A1 |
| ARG2 | arginase 2 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASS1 | argininosuccinate synthase 1 |
| ATF3 | activating transcription factor 3 |
| ATF4 | activating transcription factor 4 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CARS | cysteinyl-tRNA synthetase |
| CBS | cystathionine-beta-synthase |
| CD24 | CD24 molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CKAP4 | cytoskeleton-associated protein 4 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CSTA | cystatin A (stefin A) |
| CTSL | cathepsin L |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP5 | dual specificity phosphatase 5 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPRS | glutamyl-prolyl-tRNA synthetase |
| EREG | epiregulin |
| FAM129A | family with sequence similarity 129, member A |
| FHL2 | four and a half LIM domains 2 |
| FOSL2 | FOS-like antigen 2 |
| G0S2 | G0/G1 switch 2 |
| GAB2 | GRB2-associated binding protein 2 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GARS | glycyl-tRNA synthetase |
| GDF15 | growth differentiation factor 15 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble |
| GRB10 | growth factor receptor-bound protein 10 |
| GTPBP2 | GTP binding protein 2 |
| HBB | hemoglobin, beta |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H2AC | histone cluster 1, H2ac |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) |
| IFRD1 | interferon-related developmental regulator 1 |
| INHBB | inhibin, beta B |
| INHBE | inhibin, beta E |
| IRF9 | interferon regulatory factor 9 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| KRT15 | keratin 15, type I |
| KRT23 | keratin 23, type I |
| KRT6A | keratin 6A, type II |
| KRT81 | keratin 81, type II |
| KYNU | kynureninase |
| LAMB3 | laminin, beta 3 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LCN2 | lipocalin 2 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAP1B | microtubule-associated protein 1B |
| MARS | methionyl-tRNA synthetase |
| MB | myoglobin |
| MIR22HG | MIR22 host gene |
| MOCOS | molybdenum cofactor sulfurase |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MSMB | microseminoprotein, beta- |
| MYO15B | myosin XVB |
| NCF2 | neutrophil cytosolic factor 2 |
| NEB | nebulin |
| NLRP2 | NLR family, pyrin domain containing 2 |
| NMRK1 | nicotinamide riboside kinase 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PHGDH | phosphoglycerate dehydrogenase |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLIN2 | perilipin 2 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSAT1 | phosphoserine aminotransferase 1 |
| PYGB | phosphorylase, glycogen; brain |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGCC | regulator of cell cycle |
| RIOK3 | RIO kinase 3 |
| RND3 | Rho family GTPase 3 |
| S100A14 | S100 calcium binding protein A14 |
| S100A8 | S100 calcium binding protein A8 |
| SARS | seryl-tRNA synthetase |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SIK1 | salt-inducible kinase 1 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SMAD3 | SMAD family member 3 |
| SQSTM1 | sequestosome 1 |
| STC2 | stanniocalcin 2 |
| STX1A | syntaxin 1A (brain) |
| SULF1 | sulfatase 1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TRIB1 | tribbles pseudokinase 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSC22D3 | TSC22 domain family, member 3 |
| UPP1 | uridine phosphorylase 1 |
| VEGFA | vascular endothelial growth factor A |
| WARS | tryptophanyl-tRNA synthetase |
| XPOT | exportin, tRNA |
| YARS | tyrosyl-tRNA synthetase |
| Symbol | Name |
|---|---|
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 |
| ASF1B | anti-silencing function 1B histone chaperone |
| ATF5 | activating transcription factor 5 |
| AURKA | aurora kinase A |
| B3GNT1 | |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BST2 | bone marrow stromal cell antigen 2 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CCNA2 | cyclin A2 |
| CCNE2 | cyclin E2 |
| CCNF | cyclin F |
| CCNG1 | cyclin G1 |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDCA4 | cell division cycle associated 4 |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPA | centromere protein A |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CHEK2 | checkpoint kinase 2 |
| CKAP2 | cytoskeleton associated protein 2 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CYTL1 | cytokine-like 1 |
| DCK | deoxycytidine kinase |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EBP | emopamil binding protein (sterol isomerase) |
| EMP2 | epithelial membrane protein 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FAM111A | family with sequence similarity 111, member A |
| FANCI | Fanconi anemia, complementation group I |
| FEN1 | flap structure-specific endonuclease 1 |
| FGFR3 | fibroblast growth factor receptor 3 |
| GATA2 | GATA binding protein 2 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GTSE1 | G-2 and S-phase expressed 1 |
| H2AFX | H2A histone family, member X |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HES1 | hes family bHLH transcription factor 1 |
| HMGB3 | high mobility group box 3 |
| HMGN3 | high mobility group nucleosomal binding domain 3 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPB1 | heat shock 27kDa protein 1 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 |
| JADE2 | jade family PHD finger 2 |
| KIAA0101 | KIAA0101 |
| KIF14 | kinesin family member 14 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| KIF2C | kinesin family member 2C |
| LEPR | leptin receptor |
| LIG1 | ligase I, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| LOXL1 | lysyl oxidase-like 1 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCAM | melanoma cell adhesion molecule |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MELK | maternal embryonic leucine zipper kinase |
| MKI67 | marker of proliferation Ki-67 |
| MREG | melanoregulin |
| MSH6 | mutS homolog 6 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| MYLK | myosin light chain kinase |
| NCAPG | non-SMC condensin I complex, subunit G |
| NCAPH | non-SMC condensin I complex, subunit H |
| NSL1 | NSL1, MIS12 kinetochore complex component |
| NUP210 | nucleoporin 210kDa |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| OIP5 | Opa interacting protein 5 |
| PBK | PDZ binding kinase |
| PCNA | proliferating cell nuclear antigen |
| PLK1 | polo-like kinase 1 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPIH | peptidylprolyl isomerase H (cyclophilin H) |
| PRKD3 | protein kinase D3 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| QDPR | quinoid dihydropteridine reductase |
| QPRT | quinolinate phosphoribosyltransferase |
| RAD51 | RAD51 recombinase |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RBBP4 | retinoblastoma binding protein 4 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RMI1 | RecQ mediated genome instability 1 |
| RPA3 | replication protein A3, 14kDa |
| SEPT11 | septin 11 |
| SESN1 | sestrin 1 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SMAD1 | SMAD family member 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPAG5 | sperm associated antigen 5 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| STMN1 | stathmin 1 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TBC1D4 | TBC1 domain family, member 4 |
| TMEM109 | transmembrane protein 109 |
| TMEM97 | transmembrane protein 97 |
| TMPO | thymopoietin |
| TPX2 | TPX2, microtubule-associated |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TSPAN4 | tetraspanin 4 |
| TYMS | thymidylate synthetase |
| TYRP1 | tyrosinase-related protein 1 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UNG | uracil-DNA glycosylase |
| VRK1 | vaccinia related kinase 1 |
