| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
313 genes differentially expressed following the BRD-K33272502_DG-041_MCF7_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AARS | alanyl-tRNA synthetase |
| AHR | aryl hydrocarbon receptor |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AMOTL2 | angiomotin like 2 |
| ANXA1 | annexin A1 |
| ANXA3 | annexin A3 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATF4 | activating transcription factor 4 |
| ATF6 | activating transcription factor 6 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CADM1 | cell adhesion molecule 1 |
| CARS | cysteinyl-tRNA synthetase |
| CBS | cystathionine-beta-synthase |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CCND2 | cyclin D2 |
| CCNG2 | cyclin G2 |
| CCNI | cyclin I |
| CD163 | CD163 molecule |
| CD44 | CD44 molecule (Indian blood group) |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CELF2 | CUGBP, Elav-like family member 2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLDN3 | claudin 3 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CTSL | cathepsin L |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| EMX2 | empty spiracles homeobox 2 |
| EPRS | glutamyl-prolyl-tRNA synthetase |
| FAM129A | family with sequence similarity 129, member A |
| FOXO3 | forkhead box O3 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 |
| GARS | glycyl-tRNA synthetase |
| GATAD1 | GATA zinc finger domain containing 1 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GRB10 | growth factor receptor-bound protein 10 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HES1 | hes family bHLH transcription factor 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IARS | isoleucyl-tRNA synthetase |
| ICAM1 | intercellular adhesion molecule 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IER5 | immediate early response 5 |
| IFRD1 | interferon-related developmental regulator 1 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 |
| JUN | jun proto-oncogene |
| KCMF1 | potassium channel modulatory factor 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF6 | Kruppel-like factor 6 |
| KRT7 | keratin 7, type II |
| KRT81 | keratin 81, type II |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LCN2 | lipocalin 2 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MARS | methionyl-tRNA synthetase |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MMP7 | matrix metallopeptidase 7 |
| MXI1 | MAX interactor 1, dimerization protein |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAV2 | neuron navigator 2 |
| NCAM1 | neural cell adhesion molecule 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEBL | nebulette |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NRCAM | neuronal cell adhesion molecule |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDLIM1 | PDZ and LIM domain 1 |
| PDLIM5 | PDZ and LIM domain 5 |
| PHGDH | phosphoglycerate dehydrogenase |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRSS8 | protease, serine, 8 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RAB38 | RAB38, member RAS oncogene family |
| RAI14 | retinoic acid induced 14 |
| RAP1GAP | RAP1 GTPase activating protein |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RND3 | Rho family GTPase 3 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SARS | seryl-tRNA synthetase |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SETD5 | SET domain containing 5 |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SIK1 | salt-inducible kinase 1 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SQSTM1 | sequestosome 1 |
| SRI | sorcin |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STC2 | stanniocalcin 2 |
| TARS | threonyl-tRNA synthetase |
| TES | testin LIM domain protein |
| TGFA | transforming growth factor, alpha |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TKT | transketolase |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TPP1 | tripeptidyl peptidase I |
| TRD | T cell receptor delta locus |
| TRDV3 | T cell receptor delta variable 3 |
| TRIB1 | tribbles pseudokinase 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM16 | tripartite motif containing 16 |
| TRIM2 | tripartite motif containing 2 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN12 | tetraspanin 12 |
| TTC17 | tetratricopeptide repeat domain 17 |
| TXNRD1 | thioredoxin reductase 1 |
| UPP1 | uridine phosphorylase 1 |
| USP3 | ubiquitin specific peptidase 3 |
| VEGFA | vascular endothelial growth factor A |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| WARS | tryptophanyl-tRNA synthetase |
| WDR45 | WD repeat domain 45 |
| WSB1 | WD repeat and SOCS box containing 1 |
| XPOT | exportin, tRNA |
| YARS | tyrosyl-tRNA synthetase |
| ZBED2 | zinc finger, BED-type containing 2 |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZFP36 | ZFP36 ring finger protein |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF146 | zinc finger protein 146 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 |
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| ACOT7 | acyl-CoA thioesterase 7 |
| ADD3 | adducin 3 (gamma) |
| ADI1 | acireductone dioxygenase 1 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit |
| ASF1B | anti-silencing function 1B histone chaperone |
| ATAD2 | ATPase family, AAA domain containing 2 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| AURKB | aurora kinase B |
| B3GNT1 | |
| BAG3 | BCL2-associated athanogene 3 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BRCA1 | breast cancer 1, early onset |
| C7 | complement component 7 |
| CA12 | carbonic anhydrase XII |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCNA2 | cyclin A2 |
| CCND3 | cyclin D3 |
| CCNE2 | cyclin E2 |
| CCNF | cyclin F |
| CDC25A | cell division cycle 25A |
| CDC42 | cell division cycle 42 |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CDCA8 | cell division cycle associated 8 |
| CDK1 | cyclin-dependent kinase 1 |
| CDK2 | cyclin-dependent kinase 2 |
| CENPM | centromere protein M |
| CENPN | centromere protein N |
| CETN2 | centrin, EF-hand protein, 2 |
| CMC2 | C-x(9)-C motif containing 2 |
| CRYZ | crystallin, zeta (quinone reductase) |
| CYBA | cytochrome b-245, alpha polypeptide |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DCN | decorin |
| DCTPP1 | dCTP pyrophosphatase 1 |
| DCXR | dicarbonyl/L-xylulose reductase |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHFR | dihydrofolate reductase |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUT | deoxyuridine triphosphatase |
| EBP | emopamil binding protein (sterol isomerase) |
| ECHS1 | enoyl CoA hydratase, short chain, 1, mitochondrial |
| EMP2 | epithelial membrane protein 2 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| EXO1 | exonuclease 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM111A | family with sequence similarity 111, member A |
| FANCI | Fanconi anemia, complementation group I |
| FASN | fatty acid synthase |
| FBXO9 | F-box protein 9 |
| FEN1 | flap structure-specific endonuclease 1 |
| GHR | growth hormone receptor |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| GTSE1 | G-2 and S-phase expressed 1 |
| H2AFX | H2A histone family, member X |
| HELLS | helicase, lymphoid-specific |
| HOXC10 | homeobox C10 |
| HOXC6 | homeobox C6 |
| HSPB11 | heat shock protein family B (small), member 11 |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| KIAA0101 | KIAA0101 |
| KIF11 | kinesin family member 11 |
| LIG1 | ligase I, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MCM7 | minichromosome maintenance complex component 7 |
| MELK | maternal embryonic leucine zipper kinase |
| MICB | MHC class I polypeptide-related sequence B |
| MKI67 | marker of proliferation Ki-67 |
| MSH6 | mutS homolog 6 |
| MUC1 | mucin 1, cell surface associated |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYCBP | MYC binding protein |
| NCAPD3 | non-SMC condensin II complex, subunit D3 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| OIP5 | Opa interacting protein 5 |
| ORC6 | origin recognition complex, subunit 6 |
| PCNA | proliferating cell nuclear antigen |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PHB | prohibitin |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PKM | pyruvate kinase, muscle |
| PMPCA | peptidase (mitochondrial processing) alpha |
| PNP | purine nucleoside phosphorylase |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| POP4 | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPIF | peptidylprolyl isomerase F |
| PPIH | peptidylprolyl isomerase H (cyclophilin H) |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| RAD51 | RAD51 recombinase |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RNASEH2A | ribonuclease H2, subunit A |
| RPA3 | replication protein A3, 14kDa |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| S100A7 | S100 calcium binding protein A7 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SFPQ | splicing factor proline/glutamine-rich |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SKP1 | S-phase kinase-associated protein 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SMC2 | structural maintenance of chromosomes 2 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
| SNRPA1 | small nuclear ribonucleoprotein polypeptide A' |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa |
| SPAG5 | sperm associated antigen 5 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SRSF2 | serine/arginine-rich splicing factor 2 |
| STMN1 | stathmin 1 |
| STRA13 | stimulated by retinoic acid 13 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| SYNM | synemin, intermediate filament protein |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TFDP1 | transcription factor Dp-1 |
| TK1 | thymidine kinase 1, soluble |
| TMEM14A | transmembrane protein 14A |
| TMPO | thymopoietin |
| TMX4 | thioredoxin-related transmembrane protein 4 |
| TOB1 | transducer of ERBB2, 1 |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBB | tubulin, beta class I |
| TUBB3 | tubulin, beta 3 class III |
| TUBB4B | tubulin, beta 4B class IVb |
| TYMS | thymidylate synthetase |
| UBE2N | ubiquitin-conjugating enzyme E2N |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
| VRK1 | vaccinia related kinase 1 |
| ZWINT | ZW10 interacting kinetochore protein |
