| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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141 genes differentially expressed following the BRD-K33272502_DG-041_SKMEL28_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| A2M | alpha-2-macroglobulin |
| AARS | alanyl-tRNA synthetase |
| ANXA4 | annexin A4 |
| AQP8 | aquaporin 8 |
| AREG | amphiregulin |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASPN | asporin |
| ASS1 | argininosuccinate synthase 1 |
| ATF3 | activating transcription factor 3 |
| BMP4 | bone morphogenetic protein 4 |
| CA1 | carbonic anhydrase I |
| CA2 | carbonic anhydrase II |
| CAPN2 | calpain 2, (m/II) large subunit |
| CAST | calpastatin |
| CBS | cystathionine-beta-synthase |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CEP57 | centrosomal protein 57kDa |
| CLCA4 | chloride channel accessory 4 |
| CLIC4 | chloride intracellular channel 4 |
| COL9A3 | collagen, type IX, alpha 3 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DSP | desmoplakin |
| DUSP1 | dual specificity phosphatase 1 |
| EFHD1 | EF-hand domain family, member D1 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EPAS1 | endothelial PAS domain protein 1 |
| FHL1 | four and a half LIM domains 1 |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| FOXF2 | forkhead box F2 |
| GARS | glycyl-tRNA synthetase |
| GNAS | GNAS complex locus |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KRT18 | keratin 18, type I |
| LUM | lumican |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAP7 | microtubule-associated protein 7 |
| MARS | methionyl-tRNA synthetase |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MTSS1 | metastasis suppressor 1 |
| MYO1D | myosin ID |
| NNMT | nicotinamide N-methyltransferase |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAD21 | RAD21 homolog (S. pombe) |
| RCAN2 | regulator of calcineurin 2 |
| RGCC | regulator of cell cycle |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SPEN | spen family transcriptional repressor |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STC2 | stanniocalcin 2 |
| TARS | threonyl-tRNA synthetase |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TPD52 | tumor protein D52 |
| TRIB3 | tribbles pseudokinase 3 |
| XBP1 | X-box binding protein 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| YARS | tyrosyl-tRNA synthetase |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| Symbol | Name |
|---|---|
| ADIRF | adipogenesis regulatory factor |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AK4 | adenylate kinase 4 |
| ARGLU1 | arginine and glutamate rich 1 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BEX1 | brain expressed, X-linked 1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CBR3 | carbonyl reductase 3 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CD24 | CD24 molecule |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CORO1A | coronin, actin binding protein, 1A |
| CTSH | cathepsin H |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ERI2 | ERI1 exoribonuclease family member 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXC6 | homeobox C6 |
| HSPB8 | heat shock 22kDa protein 8 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IL7R | interleukin 7 receptor |
| JADE2 | jade family PHD finger 2 |
| LBR | lamin B receptor |
| LTF | lactotransferrin |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MMD | monocyte to macrophage differentiation-associated |
| MNDA | myeloid cell nuclear differentiation antigen |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
| NKG7 | natural killer cell granule protein 7 |
| NPY | neuropeptide Y |
| NPY1R | neuropeptide Y receptor Y1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB15 | RAB15, member RAS oncogene family |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RNF167 | ring finger protein 167 |
| RPS26 | ribosomal protein S26 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SORD | sorbitol dehydrogenase |
| STOM | stomatin |
| STX1A | syntaxin 1A (brain) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TLR4 | toll-like receptor 4 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM164 | transmembrane protein 164 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TRBC1 | T cell receptor beta constant 1 |
| TRIB2 | tribbles pseudokinase 2 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 |
