| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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151 genes differentially expressed following the BRD-K33272502_DG-041_U937_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AARS | alanyl-tRNA synthetase |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASS1 | argininosuccinate synthase 1 |
| ATF4 | activating transcription factor 4 |
| AUTS2 | autism susceptibility candidate 2 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BLNK | B-cell linker |
| CAPG | capping protein (actin filament), gelsolin-like |
| CARS | cysteinyl-tRNA synthetase |
| CBR3 | carbonyl reductase 3 |
| CBS | cystathionine-beta-synthase |
| CCNG2 | cyclin G2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLIC4 | chloride intracellular channel 4 |
| CLU | clusterin |
| COG5 | component of oligomeric golgi complex 5 |
| COL3A1 | collagen, type III, alpha 1 |
| CRYAB | crystallin, alpha B |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 |
| DACH1 | dachshund family transcription factor 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DUOX2 | dual oxidase 2 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EIF5 | eukaryotic translation initiation factor 5 |
| EREG | epiregulin |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| EZR | ezrin |
| FHL1 | four and a half LIM domains 1 |
| GAB2 | GRB2-associated binding protein 2 |
| H1F0 | H1 histone family, member 0 |
| HIST1H4C | histone cluster 1, H4c |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IL15 | interleukin 15 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KLF6 | Kruppel-like factor 6 |
| KLHDC2 | kelch domain containing 2 |
| KLK5 | kallikrein-related peptidase 5 |
| KYNU | kynureninase |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LMO4 | LIM domain only 4 |
| MAP7 | microtubule-associated protein 7 |
| MARS | methionyl-tRNA synthetase |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDLIM5 | PDZ and LIM domain 5 |
| PLA2G16 | phospholipase A2, group XVI |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RGS13 | regulator of G-protein signaling 13 |
| RGS5 | regulator of G-protein signaling 5 |
| RNF114 | ring finger protein 114 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMC4 | structural maintenance of chromosomes 4 |
| STC2 | stanniocalcin 2 |
| TARS | threonyl-tRNA synthetase |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TRIB3 | tribbles pseudokinase 3 |
| TSC22D3 | TSC22 domain family, member 3 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| WARS | tryptophanyl-tRNA synthetase |
| XIST | X inactive specific transcript (non-protein coding) |
| YPEL5 | yippee-like 5 (Drosophila) |
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| C3 | complement component 3 |
| CCDC86 | coiled-coil domain containing 86 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CCNF | cyclin F |
| CD200 | CD200 molecule |
| CD3EAP | CD3e molecule, epsilon associated protein |
| COPS7A | COP9 signalosome subunit 7A |
| CYTL1 | cytokine-like 1 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| EGR3 | early growth response 3 |
| EMP2 | epithelial membrane protein 2 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM57A | family with sequence similarity 57, member A |
| FASN | fatty acid synthase |
| GRPEL1 | GrpE-like 1, mitochondrial (E. coli) |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPE1 | heat shock 10kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| INSIG1 | insulin induced gene 1 |
| KAZN | kazrin, periplakin interacting protein |
| LAGE3 | L antigen family, member 3 |
| LAMC2 | laminin, gamma 2 |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MARCKSL1 | MARCKS-like 1 |
| MAT2A | methionine adenosyltransferase II, alpha |
| METTL13 | methyltransferase like 13 |
| MMP1 | matrix metallopeptidase 1 |
| MREG | melanoregulin |
| MSLN | mesothelin |
| NOP16 | NOP16 nucleolar protein |
| NSG1 | neuron specific gene family member 1 |
| PLAT | plasminogen activator, tissue |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PNP | purine nucleoside phosphorylase |
| PODXL | podocalyxin-like |
| PPIF | peptidylprolyl isomerase F |
| PRAME | preferentially expressed antigen in melanoma |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 |
| PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) |
| QPRT | quinolinate phosphoribosyltransferase |
| RBP1 | retinol binding protein 1, cellular |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRAGD | Ras-related GTP binding D |
| SACS | sacsin molecular chaperone |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SHQ1 | SHQ1, H/ACA ribonucleoprotein assembly factor |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SPON1 | spondin 1, extracellular matrix protein |
| SRSF2 | serine/arginine-rich splicing factor 2 |
| SST | somatostatin |
| STAP2 | signal transducing adaptor family member 2 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TEX10 | testis expressed 10 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TYRP1 | tyrosinase-related protein 1 |
